{"id":"W2137127609","doi":"10.1002/pd.4718","title":"Current controversies in prenatal diagnosis 2: should a fetal exome be used in the assessment of a dysmorphic or malformed fetus?","year":2015,"lang":"en","type":"article","venue":"Prenatal Diagnosis","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute for Health and Care Research","keywords":"Exome sequencing; Medicine; Exome; Prenatal diagnosis; Pregnancy; Fetus; Genetic testing; Obstetrics; Genetic counseling; Pediatrics; Genetics; Mutation; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04348136,0.0007609298,0.001813618,0.003641749,0.002555228,0.0043176,0.004270182,0.01252233,0.003736963],"category_scores_gemma":[0.1330332,0.0007249808,0.001034447,0.002192658,0.01135956,0.01137725,0.002869852,0.01488175,0.002488967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002917733,"about_ca_system_score_gemma":0.006483225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006961431,"about_ca_topic_score_gemma":0.007789748,"domain_scores_codex":[0.986773,0.005736237,0.002399547,0.001729444,0.002840979,0.0005208303],"domain_scores_gemma":[0.8370032,0.1306018,0.004850184,0.002407093,0.02223489,0.002903007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003791288,0.00008687983,0.011608,0.005622406,0.0002213537,0.001593902,0.002366377,0.0003783286,0.000834768,0.03427995,0.2454039,0.6972249],"study_design_scores_gemma":[0.0001608358,0.0002584235,0.01226185,0.03350255,0.0005905787,0.01258808,0.009138769,0.001303746,0.001180672,0.1737268,0.7549109,0.000376946],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001373172,0.2342864,0.002436762,0.7499546,0.0093435,0.00002014095,0.0001294653,0.00006926175,0.002386723],"genre_scores_gemma":[0.0543459,0.5103405,0.01282446,0.3300034,0.09048005,0.0001093184,0.0003693176,0.0001651889,0.001361998],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04348136,"threshold_uncertainty_score":0.2299542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1179105055629519,"score_gpt":0.3669032780076434,"score_spread":0.2489927724446916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}