{"id":"W2137129298","doi":"10.4161/cc.23178","title":"Intrinsically disordered proteins and conformational noise","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Department of Science and Technology, Ministry of Science and Technology, India; Jawaharlal Nehru Centre for Advanced Scientific Research; National Science Foundation","keywords":"Intrinsically disordered proteins; Biology; Chromatin; Conformational change; Computational biology; Protein structure; Epigenetics; Genetics; Cell biology; Biophysics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002300604,0.0002908605,0.0002997629,0.0004116506,0.0003445414,0.0006984323,0.0003991066,0.0005545087,0.0007632712],"category_scores_gemma":[0.0008605374,0.0001759389,0.0002084309,0.0002888148,0.001034282,0.0009281018,0.00056484,0.000425665,0.00011032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005515539,"about_ca_system_score_gemma":0.000313426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066936,"about_ca_topic_score_gemma":0.0007723832,"domain_scores_codex":[0.9998222,0.00005613817,0.000006118516,0.00004893084,0.00003892559,0.0000276981],"domain_scores_gemma":[0.9995023,0.0002273346,0.0001281574,0.0000521241,0.00002893558,0.00006112456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002834538,0.0001112827,0.01002818,0.0002234315,0.00007733572,0.0008955761,0.0002802733,0.4669485,0.1594795,0.3422212,0.001093284,0.01835794],"study_design_scores_gemma":[0.0000255193,0.00009806722,0.005940674,0.00002431657,0.00002407052,0.0003723996,0.0001525928,0.713681,0.022897,0.2487258,0.008013282,0.00004529903],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8110663,0.0026856,0.1714464,0.0009912109,0.0001065575,0.0000300205,0.0003322638,0.0004647442,0.01287703],"genre_scores_gemma":[0.9925653,0.0005312517,0.005529554,0.00005542367,0.00001919763,0.00001908546,0.00008148764,0.00002143443,0.001177342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001066936,"threshold_uncertainty_score":0.004001796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003963654197530341,"score_gpt":0.1936319049421191,"score_spread":0.1896682507445888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}