{"id":"W2137140199","doi":"10.1016/j.mehy.2007.09.015","title":"An evolutionary approach to major histocompatibility diversity based on allele supertypes","year":2007,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Allele; Biology; Major histocompatibility complex; Genetics; Balancing selection; Loss of heterozygosity; Human leukocyte antigen; Evolutionary biology; Antigen; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002396356,0.0004153961,0.0003425565,0.0009918932,0.0008724664,0.00106351,0.001278283,0.001279697,0.003603067],"category_scores_gemma":[0.002389353,0.0001521736,0.0003050111,0.0004878831,0.004726175,0.001911068,0.0008185983,0.001969828,0.0003394963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006828832,"about_ca_system_score_gemma":0.0004550538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001786838,"about_ca_topic_score_gemma":0.000159467,"domain_scores_codex":[0.9994819,0.0002307837,0.00002098282,0.00009738291,0.0001119674,0.00005703354],"domain_scores_gemma":[0.9987152,0.0006374508,0.0001487126,0.0001296977,0.0002121751,0.0001568569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001840386,0.00006190928,0.005122885,0.0001253594,0.00004605895,0.0009793052,0.0009895174,0.003451442,0.007026359,0.9388201,0.00130048,0.04189273],"study_design_scores_gemma":[0.00009269882,0.0003016411,0.005526378,0.00006786027,0.00005737047,0.002129814,0.000759127,0.01485516,0.002825544,0.9558926,0.01745348,0.00003817392],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5253195,0.006508833,0.3156405,0.04372463,0.001698881,0.000181417,0.0002578839,0.0001846674,0.1064836],"genre_scores_gemma":[0.9663249,0.001404772,0.0244411,0.002330397,0.0008399606,0.00005445949,0.00007034943,0.00001720965,0.004516895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003603067,"threshold_uncertainty_score":0.01267332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02575315739614764,"score_gpt":0.2444542526541492,"score_spread":0.2187010952580016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}