{"id":"W2137179442","doi":"10.1152/japplphysiol.00098.2012","title":"Phrenic long-term facilitation after acute intermittent hypoxia requires spinal ERK activation but not TrkB synthesis","year":2012,"lang":"en","type":"article","venue":"Journal of Applied Physiology","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Alberta Innovates - Health Solutions; National Institute of General Medical Sciences; Francis Family Foundation","keywords":"Tropomyosin receptor kinase B; MAPK/ERK pathway; Intermittent hypoxia; PI3K/AKT/mTOR pathway; Protein kinase B; Biology; Brain-derived neurotrophic factor; Neurotrophic factors; Pharmacology; Receptor; Signal transduction; Medicine; Internal medicine; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008748906,0.0002072711,0.0001816002,0.00007929585,0.00008641976,0.0001192574,0.0001318198,0.0001411339,0.0009767156],"category_scores_gemma":[0.0001025672,0.00009077798,0.0002656398,0.00004453597,0.0001816106,0.0001619579,0.0001396992,0.0003938575,0.0001399814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000191892,"about_ca_system_score_gemma":0.0002006999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001127296,"about_ca_topic_score_gemma":0.002323916,"domain_scores_codex":[0.9999342,0.000006512279,0.000006009481,0.00001194055,0.00001248534,0.00002890772],"domain_scores_gemma":[0.9999062,0.00001325338,0.00003311995,0.0000106455,0.00001059951,0.00002620386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002660493,0.00002396319,0.0001473225,0.00002975384,0.000004071651,0.00005563644,0.00001045585,0.00003336613,0.9984075,0.0000389856,0.00002193365,0.0009609986],"study_design_scores_gemma":[0.00005434368,0.001129834,0.04081928,0.00001709326,0.00002825229,0.0003178835,0.00005558971,0.001177246,0.9555132,0.00006648004,0.000812685,0.000008138259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976248,0.00047418,0.0008063835,0.00004878802,0.00001599858,0.00001626525,0.0001403389,0.00003794624,0.0008351646],"genre_scores_gemma":[0.997327,0.0003549138,0.0008734672,0.00002853283,0.000009374215,0.00003350916,0.0002302468,0.0000063792,0.00113659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001127296,"threshold_uncertainty_score":0.003267407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0389383009127975,"score_gpt":0.2959835785807752,"score_spread":0.2570452776679777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}