{"id":"W2137232836","doi":"10.1021/cb500499x","title":"RNA Mango Aptamer-Fluorophore: A Bright, High-Affinity Complex for RNA Labeling and Tracking","year":2014,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":453,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"RNA; Aptamer; Fluorophore; Fluorescence; Biophysics; Chemistry; Biochemistry; Biology; Molecular biology; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003676239,0.0003083372,0.0003249076,0.0002585837,0.0002437292,0.0003149561,0.0004044532,0.0005342044,0.000877907],"category_scores_gemma":[0.0002497942,0.0002493609,0.00017308,0.0001632205,0.0002839053,0.0003107228,0.0002746578,0.0005389058,0.0004696603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004727918,"about_ca_system_score_gemma":0.0002518496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005912954,"about_ca_topic_score_gemma":0.001328521,"domain_scores_codex":[0.9997217,0.00004694313,0.00001583341,0.00007793803,0.00009408582,0.00004352076],"domain_scores_gemma":[0.9998472,0.00004859833,0.00002692243,0.00001673441,0.00001667846,0.00004382813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001602447,0.000006864685,0.00004615777,0.00001349333,0.00000182105,0.00001458167,0.000006015524,0.00005089784,0.9993373,0.0001023809,0.00002999873,0.0003744838],"study_design_scores_gemma":[0.000007724832,0.00004291551,0.0003964498,0.000002054347,0.000004790149,0.0001045485,0.000002961882,0.00127381,0.9965385,0.00003430982,0.001585925,0.000005997991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8622386,0.001608045,0.1310475,0.0004626584,0.00008236407,0.0002306447,0.0003277878,0.0006874381,0.003314826],"genre_scores_gemma":[0.8822823,0.0006175388,0.1103997,0.0002253059,0.00002272133,0.0001662868,0.0005272009,0.0001072511,0.005651718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000877907,"threshold_uncertainty_score":0.003430426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02080928313015288,"score_gpt":0.2576458321678973,"score_spread":0.2368365490377444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}