{"id":"W2137283728","doi":"10.1128/mcb.21.7.2384-2392.2001","title":"Establishment and Maintenance of DNA Methylation Patterns in Mouse <i>Ndn</i> : Implications for Maintenance of Imprinting in Target Genes of the Imprinting Center","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Division of Materials Research","keywords":"Genomic imprinting; Biology; Imprinting (psychology); DNA methylation; Epigenetics; Genetics; Blastocyst; Methylation; Gene; CpG site; Bisulfite sequencing; DNA demethylation; Oocyte; RNA-Directed DNA Methylation; Molecular biology; Embryo; Embryogenesis; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000160939,0.0001548293,0.000121466,0.0002767604,0.0001678482,0.0002606139,0.0003426652,0.0002332652,0.0006164599],"category_scores_gemma":[0.0001813681,0.0001853365,0.0001973839,0.000083834,0.0002659378,0.0002897335,0.0002539892,0.0003381807,0.0002333387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003947155,"about_ca_system_score_gemma":0.0002186413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00200399,"about_ca_topic_score_gemma":0.003058674,"domain_scores_codex":[0.9998842,0.00000864527,0.00001036372,0.00004384062,0.00003023216,0.00002260558],"domain_scores_gemma":[0.9998404,0.00001465771,0.00005209376,0.00002931616,0.0000242295,0.00003939476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005071432,0.000004811539,0.002380957,0.00001477719,0.000004512249,0.00003185286,0.00003805202,0.00002927058,0.9955592,0.0002057777,0.00001483171,0.001665211],"study_design_scores_gemma":[0.00001685031,0.0001748952,0.1200951,0.00001406256,0.00003246539,0.0005098886,0.00008599851,0.0005316666,0.8746417,0.0002830819,0.003603262,0.00001113003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918718,0.001280619,0.004417921,0.00007282242,0.0000109689,0.00001782355,0.000548178,0.00007476773,0.001704989],"genre_scores_gemma":[0.992765,0.0007029298,0.002265336,0.00005848454,0.000004773745,0.00003895011,0.0008502536,0.0000367657,0.003277527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00200399,"threshold_uncertainty_score":0.00398463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007802827356174907,"score_gpt":0.2299571349854685,"score_spread":0.2221543076292936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}