{"id":"W2137341681","doi":"10.1093/nass/nrm179","title":"Enzymatic Incorporation of 2-Amino-6-Vinylpurine Derivative","year":2007,"lang":"en","type":"article","venue":"Nucleic Acids Symposium Series","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Nucleoside; Nucleotide; Cytidine; Purine; DNA; Chemistry; Biochemistry; Enzyme; Nucleic acid; Duplex (building); RNA; Polymerase; Nucleobase; Nucleoside triphosphate; Derivative (finance); Stereochemistry; Combinatorial chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002476172,0.0002240182,0.000232071,0.00005163374,0.00008786114,0.0000173924,0.0002576525,0.000220587,0.00006206978],"category_scores_gemma":[0.00006961194,0.0002201616,0.00009769304,0.0001538874,0.000273853,0.00002094882,0.0001587644,0.00009652242,0.00001374526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002366154,"about_ca_system_score_gemma":0.00005764932,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008162484,"about_ca_topic_score_gemma":0.00001497839,"domain_scores_codex":[0.9987373,0.00002440055,0.000424377,0.0003160097,0.0002103721,0.0002874979],"domain_scores_gemma":[0.9990377,0.0000157211,0.0002400155,0.0004470475,0.0001593946,0.000100164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002319066,0.00007975529,0.005769993,0.00008672,0.00005396709,0.00000521259,0.000256355,0.000008236857,0.9917105,0.0005473592,0.000730235,0.0005197426],"study_design_scores_gemma":[0.0004097353,0.0003716912,0.004346279,0.00002475261,0.00002516218,0.0000418432,0.0004856314,0.000008974811,0.9834821,0.0002582239,0.01030682,0.0002388131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827286,0.0001430197,0.002125918,0.0002058766,0.0001573321,0.0001425863,0.00001757606,0.00003511569,0.01444399],"genre_scores_gemma":[0.994126,0.0000821849,0.003495499,0.0001288944,0.0002546587,0.00000837192,0.0001391569,0.00003814526,0.001727081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01271691,"threshold_uncertainty_score":0.8977928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005747743931011248,"score_gpt":0.2227924982859097,"score_spread":0.2170447543548985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}