{"id":"W2137467802","doi":"10.1056/nejmoa1209096","title":"Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy","year":2012,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":2795,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Juravinski Cancer Centre; Université de Montréal","funders":"National Cancer Institute","keywords":"Prednisone; Medicine; Abiraterone acetate; Hazard ratio; Prostate cancer; Internal medicine; Interim analysis; Urology; Chemotherapy; Oncology; Surgery; Cancer; Gastroenterology; Androgen deprivation therapy; Randomized controlled trial; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001078881,0.0003098158,0.001258134,0.000262826,0.0001961056,0.0002558981,0.0002906212,0.0002377554,0.0009493061],"category_scores_gemma":[0.002134355,0.0001454935,0.0004555247,0.0004258375,0.0003770081,0.0001777804,0.0001999565,0.0007031102,0.0001594772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000406487,"about_ca_system_score_gemma":0.0007605017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008715214,"about_ca_topic_score_gemma":0.00222306,"domain_scores_codex":[0.9994387,0.0002721428,0.00005669215,0.00005886781,0.0001179375,0.00005561175],"domain_scores_gemma":[0.999046,0.0003690431,0.0002543246,0.00006536145,0.00005023087,0.000214971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4581909,0.008702243,0.05492571,0.004272829,0.002054663,0.001137299,0.0003457077,0.004538404,0.04680671,0.0003949247,0.002146049,0.4164846],"study_design_scores_gemma":[0.2135656,0.5973828,0.1489709,0.0005324236,0.002763973,0.005189903,0.0001511533,0.002937278,0.0130085,0.001199586,0.01424434,0.00005357253],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788743,0.01935238,0.0003227958,0.0002024373,0.0001044578,0.0001436684,0.0001017678,0.0000272568,0.0008709675],"genre_scores_gemma":[0.9945774,0.004517371,0.0002974905,0.00008885005,0.0001159371,0.00006324558,0.00009306212,0.000002306079,0.0002443736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001258134,"threshold_uncertainty_score":0.005705774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04024826831729372,"score_gpt":0.3675862686758338,"score_spread":0.3273380003585401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}