{"id":"W2137490801","doi":"10.1093/nar/gks993","title":"ClusterMine360: a database of microbial PKS/NRPS biosynthesis","year":2012,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Genomics; University of Ottawa","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; University of Ottawa","keywords":"Biology; Polyketide synthase; Polyketide; Gene; Database; Gene cluster; Ribosomal RNA; Annotation; Consistency (knowledge bases); Computational biology; Genetics; Biosynthesis; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002205781,0.0002030134,0.000449954,0.0004669835,0.0001735129,0.0000267342,0.0003523972,0.0002113138,0.002491046],"category_scores_gemma":[0.001512934,0.0001487866,0.0001593957,0.0008106289,0.000483744,0.0002434672,0.0004047031,0.0006351959,0.00053582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001116226,"about_ca_system_score_gemma":0.0001525178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001712439,"about_ca_topic_score_gemma":0.000007896148,"domain_scores_codex":[0.9972486,0.0002516149,0.000408772,0.0003995958,0.0007446118,0.0009468034],"domain_scores_gemma":[0.9979352,0.0002876507,0.00007911062,0.000867734,0.0004513377,0.0003789239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005458503,0.000505003,0.003204728,0.0003835971,0.00006703017,0.00001648029,0.0002485106,2.998509e-8,0.9391979,0.0001404946,0.03873546,0.01695491],"study_design_scores_gemma":[0.0007245083,0.0002375461,0.005929061,0.0003056174,0.00007096464,0.0001332824,0.0002203692,0.0000232272,0.8961437,0.00001203803,0.09600633,0.0001933329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883896,0.001089245,0.0000113287,0.003720315,0.0002016912,0.0006495516,0.0001263115,0.00005222545,0.005759751],"genre_scores_gemma":[0.9918105,0.000257727,0.003316267,0.0002323061,0.0009825499,0.000002684857,0.00003791358,0.00004783603,0.003312209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05727086,"threshold_uncertainty_score":0.9984208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06706502736086647,"score_gpt":0.3511968865972269,"score_spread":0.2841318592363604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}