{"id":"W2137517777","doi":"10.1128/mcb.00525-13","title":"Casein Kinase 2 Associates with the Yeast Chromatin Reassembly Factor Spt2/Sin1 To Regulate Its Function in the Repression of Spurious Transcription","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Nucleosome; Chromatin; Histone; Cell biology; Psychological repression; Casein kinase 2; Transcription factor; Casein kinase 1; Phosphorylation; Saccharomyces cerevisiae; Histone code; Transcription (linguistics); Biochemistry; DNA; Yeast; Protein kinase A; Gene; Gene expression; Mitogen-activated protein kinase kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446542,0.0008525492,0.0002283621,0.0002460289,0.0002141739,0.0004906785,0.0003296627,0.0002129103,0.001441003],"category_scores_gemma":[0.0001320939,0.000331514,0.0002315429,0.0001989979,0.0002705617,0.0002854077,0.0004708064,0.0003943162,0.0009977886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006904152,"about_ca_system_score_gemma":0.0001748645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004171541,"about_ca_topic_score_gemma":0.0008451694,"domain_scores_codex":[0.9998715,0.0000143883,0.000007991975,0.00005098259,0.00002995055,0.00002525694],"domain_scores_gemma":[0.9999056,0.000009630749,0.00003309375,0.00001092954,0.00001122907,0.00002944481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008649442,0.00001219168,0.0004357008,0.00003932035,0.000007370846,0.00006580066,0.000005757543,0.0001320118,0.9983676,0.0001010979,0.00005874542,0.0006878379],"study_design_scores_gemma":[0.00002678537,0.00006338207,0.01306853,0.000007222451,0.00001686119,0.0003562891,0.00001803519,0.00356124,0.9794655,0.0001381584,0.003270641,0.000007375374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811867,0.006436001,0.00873613,0.0001641286,0.00008218113,0.00002711406,0.0004011999,0.0002698272,0.002696687],"genre_scores_gemma":[0.9911935,0.001098589,0.002194658,0.00004856484,0.00002096773,0.00002175374,0.0009378958,0.00007464073,0.004409631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001441003,"threshold_uncertainty_score":0.005009353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004736488810375647,"score_gpt":0.195615408779763,"score_spread":0.1908789199693874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}