{"id":"W2137640482","doi":"10.1042/bj20081888","title":"Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid <i>in vivo</i>","year":2009,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Lysophosphatidic acid; Dephosphorylation; Autotaxin; Extracellular; Catabolism; In vivo; Phosphatidic acid; Biochemistry; Cell growth; Biology; Phosphatase; Angiogenesis; Alkaline phosphatase; Enzyme; Cell biology; Chemistry; Phospholipid; Cancer research; Receptor; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004886394,0.0003378016,0.0003421311,0.00009432046,0.0001305997,0.0001072715,0.0005926391,0.0003229681,0.0001318588],"category_scores_gemma":[0.0002222127,0.0003099478,0.0002317886,0.000316022,0.0001033545,0.00001764457,0.00009089036,0.0004186555,0.00002611448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003650689,"about_ca_system_score_gemma":0.0001475951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004993603,"about_ca_topic_score_gemma":9.797011e-7,"domain_scores_codex":[0.9978905,0.00006958432,0.0005748972,0.0004841144,0.0003339644,0.0006469004],"domain_scores_gemma":[0.9988053,0.00001373474,0.0001969877,0.0004742223,0.0001246671,0.0003851302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003473086,0.0001789739,0.0009439518,0.00000720497,0.00002822853,0.00006589828,0.00003765481,0.00001370832,0.9887972,0.00007354037,0.006626711,0.002879604],"study_design_scores_gemma":[0.001350395,0.0002419684,0.0002506347,0.00005350175,0.000033769,0.000253514,0.00002780254,0.00009654096,0.9545802,0.0002383681,0.04250325,0.0003700083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9313215,0.06669892,0.0004919447,0.0003523363,0.000660171,0.000126382,0.000007262324,0.00002259484,0.0003189055],"genre_scores_gemma":[0.9902636,0.004184625,0.002653492,0.0009767276,0.001496989,0.00000399892,0.0000286829,0.00003572323,0.0003562074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0625143,"threshold_uncertainty_score":0.9999353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008713691780007714,"score_gpt":0.234811701639496,"score_spread":0.2260980098594883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}