{"id":"W2137678049","doi":"10.1016/j.amjopharm.2012.11.002","title":"Use of Rivastigmine or Galantamine and Risk of Adverse Cardiac Events: A Database Study from the Netherlands","year":2012,"lang":"en","type":"article","venue":"˜The œAmerican journal of geriatric pharmacotherapy","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research; Top Institute Pharma; Novo Nordisk; Ministerie van Volksgezondheid, Welzijn en Sport; Universiteit Utrecht; GlaxoSmithKline","keywords":"Medicine; Galantamine; Hazard ratio; Rivastigmine; Adverse effect; Incidence (geometry); Internal medicine; Cohort; Discontinuation; Proportional hazards model; Cohort study; Confidence interval; Tolerability; Cardiology; Donepezil; Dementia; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001000869,0.0004363356,0.00115862,0.001014348,0.0003857483,0.001662243,0.0008620211,0.0008173146,0.002740219],"category_scores_gemma":[0.004329557,0.0007098124,0.001559934,0.002456693,0.0004526083,0.001097786,0.0006485117,0.0005413853,0.0003649977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001224828,"about_ca_system_score_gemma":0.001098248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03880812,"about_ca_topic_score_gemma":0.04812169,"domain_scores_codex":[0.9987405,0.0004043901,0.000264457,0.0003010578,0.0001759389,0.0001136851],"domain_scores_gemma":[0.9976286,0.0008482939,0.0009359593,0.0001818239,0.0002015159,0.0002038956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004233005,0.0003550301,0.9805616,0.0006465487,0.003896866,0.001428682,0.000727699,0.0002476992,0.0006799872,0.0003077361,0.001477279,0.005437994],"study_design_scores_gemma":[0.001726113,0.0004365053,0.985598,0.0002279967,0.003353675,0.002025908,0.001460051,0.001059892,0.0002828735,0.0001828606,0.003569745,0.00007625296],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931563,0.002123331,0.0001847847,0.0001351336,0.00001835502,0.00005971614,0.003325532,0.000003858247,0.0009929255],"genre_scores_gemma":[0.9923868,0.001791136,0.000338949,0.0002137896,0.00003012857,0.0001278366,0.004307745,0.00001921427,0.0007843259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03880812,"threshold_uncertainty_score":0.07716441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03130728071903836,"score_gpt":0.3445457636643336,"score_spread":0.3132384829452952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}