{"id":"W2137688247","doi":"10.1016/j.immuni.2013.09.007","title":"Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure","year":2013,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":654,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Biology; Antibody; CXCR5; Antigen; Cell; Immunology; Molecular biology; B cell; Biochemistry; Germinal center","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001950741,0.0003441927,0.0003742288,0.0005191806,0.0002713279,0.0008758156,0.0002428484,0.0005297157,0.01094995],"category_scores_gemma":[0.0002595192,0.0002603574,0.0002361849,0.0001537502,0.0002332174,0.0006060379,0.0002753899,0.001845539,0.001980288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000347584,"about_ca_system_score_gemma":0.0002034023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005707023,"about_ca_topic_score_gemma":0.0009663306,"domain_scores_codex":[0.9997144,0.00003698459,0.00001670897,0.00006388829,0.00004097376,0.0001270469],"domain_scores_gemma":[0.9997332,0.00004114702,0.00004465134,0.00002876557,0.00002632724,0.000125904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006129544,0.00006643732,0.001817157,0.00009110015,0.00001062297,0.0003846786,0.00006736055,0.00005329496,0.9893131,0.0006867468,0.0006828688,0.006213877],"study_design_scores_gemma":[0.0002072086,0.001024514,0.06195087,0.00008363942,0.00008039016,0.003497093,0.0004404948,0.003378929,0.9135953,0.0007771414,0.01493715,0.00002731332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827476,0.002631358,0.005468179,0.0002540929,0.0001966737,0.00008902801,0.0008671731,0.0003883751,0.007357466],"genre_scores_gemma":[0.9821059,0.0006986154,0.004950555,0.0002221778,0.0002253181,0.00008617871,0.0009404367,0.0001008925,0.01066985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01094995,"threshold_uncertainty_score":0.03663123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431135902189584,"score_gpt":0.247176785949416,"score_spread":0.2328654269275202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}