{"id":"W2137688247","doi":"10.1016/j.immuni.2013.09.007","title":"Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure","year":2013,"lang":"en","type":"article","venue":"Immunity","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":654,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Biology; Antibody; CXCR5; Antigen; Cell; Immunology; Molecular biology; B cell; Biochemistry; Germinal center","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007808498,0.0005145855,0.0006773486,0.0002633683,0.0009323816,0.00009721149,0.0006245908,0.0008092171,0.0007425674],"category_scores_gemma":[0.0001592309,0.0004687225,0.0001602432,0.0002965734,0.0006073663,0.0004309173,0.0005642379,0.001398323,0.001686847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000604323,"about_ca_system_score_gemma":0.0001450324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002642397,"about_ca_topic_score_gemma":0.00005778672,"domain_scores_codex":[0.9961818,0.001579802,0.0005465357,0.0006612687,0.00008321734,0.0009473857],"domain_scores_gemma":[0.9978048,0.0004867683,0.0004646006,0.001011139,0.0001561408,0.00007661418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002830657,0.0005527372,0.00711113,0.00008052032,0.0001958428,0.0000200063,0.001347363,8.912777e-7,0.9781844,0.00001305491,0.0004322035,0.01177875],"study_design_scores_gemma":[0.001639874,0.0005784531,0.0734612,0.0000650747,0.00006629871,0.0001878678,0.0003144559,0.00001339252,0.9159312,0.0001712078,0.007036223,0.0005347184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991322,0.004450751,0.00005904063,0.0002632331,0.0007149527,0.0009169615,0.00005765219,0.0002439415,0.001971497],"genre_scores_gemma":[0.9938236,0.0004775129,0.0002285044,0.00008740334,0.0000389901,0.00005149614,0.0001354569,0.00005695429,0.005100057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06635007,"threshold_uncertainty_score":0.9997764,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431135902189584,"score_gpt":0.247176785949416,"score_spread":0.2328654269275202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}