{"id":"W2137693354","doi":"10.1189/jlb.1112579","title":"Leukocyte-specific protein 1 links TNF receptor-associated factor 1 to survival signaling downstream of 4-1BB in T cells","year":2013,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Université de Montréal; Cole Foundation; Leukemia and Lymphoma Society of Canada; University of Toronto; Canadian Cancer Society; Leukemia and Lymphoma Society","keywords":"Biology; Cell biology; T cell; MAPK/ERK pathway; Signal transduction; Tumor necrosis factor alpha; Signal transducing adaptor protein; Cancer research; Cytotoxic T cell; CD8; Immunology; Immune system; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001398942,0.0005776941,0.0001927693,0.0002628676,0.0002139367,0.0002896211,0.0001880484,0.0002992338,0.001401781],"category_scores_gemma":[0.0000940297,0.000130427,0.0002315762,0.0002091918,0.0001916636,0.0001903035,0.0003014679,0.0006501117,0.0007266298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003553383,"about_ca_system_score_gemma":0.0002003047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002588927,"about_ca_topic_score_gemma":0.0002727406,"domain_scores_codex":[0.999849,0.00003178032,0.00001139061,0.00002724622,0.00003973863,0.00004080021],"domain_scores_gemma":[0.9999245,0.000004426767,0.00003380744,0.000006082731,0.000008498311,0.00002262193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001037022,0.00001655815,0.0001512136,0.00004249305,0.00000351607,0.00007693772,0.000008560856,0.00003876357,0.9986942,0.00008630803,0.00003583601,0.0007418477],"study_design_scores_gemma":[0.00003885607,0.0003147481,0.0116012,0.00001718952,0.00002791612,0.00085176,0.00004067474,0.00101144,0.9808772,0.0003520889,0.004859766,0.000007249766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884099,0.005097492,0.003971994,0.0002415113,0.00006676093,0.00003261363,0.0005286461,0.000118297,0.0015327],"genre_scores_gemma":[0.9925545,0.002352154,0.001583818,0.00007249933,0.00002102908,0.00003041774,0.0006960403,0.00001062155,0.002678904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001401781,"threshold_uncertainty_score":0.004689455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02021872974655855,"score_gpt":0.2462248336822887,"score_spread":0.2260061039357301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}