{"id":"W2137712172","doi":"10.4049/jimmunol.181.3.1887","title":"Bilirubin Possesses Powerful Immunomodulatory Activity and Suppresses Experimental Autoimmune Encephalomyelitis","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Bilirubin; Experimental autoimmune encephalomyelitis; Immune system; T cell; Immunology; Biology; In vivo; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003070117,0.0001795899,0.0002697578,0.00006326976,0.000163261,0.0000121477,0.0003528759,0.0001444078,0.00006082918],"category_scores_gemma":[0.00009318128,0.0001284588,0.000109291,0.00006665996,0.0005613267,0.00001973111,0.0001845015,0.0002416847,0.000005568799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002274252,"about_ca_system_score_gemma":0.000178573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008700285,"about_ca_topic_score_gemma":0.000005505968,"domain_scores_codex":[0.9988768,0.0002659163,0.0003225786,0.0001462977,0.0001293809,0.0002589888],"domain_scores_gemma":[0.9991416,0.00005668927,0.0002609928,0.0003674731,0.0001221766,0.00005106636],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004819558,0.0001017097,0.0005174521,0.000003692629,0.0001799012,0.00003396471,0.0003458141,0.000008808809,0.9970328,0.00001567675,0.0003924767,0.0008857708],"study_design_scores_gemma":[0.0007978655,0.001005867,0.1018929,0.00001270668,0.00002434119,0.003693308,0.0006108433,0.000003372672,0.8856788,0.00002607989,0.00610447,0.0001494837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9595371,0.03948435,0.00007804806,0.0002299711,0.0003187837,0.00007774942,0.000005050465,0.000006494222,0.0002624754],"genre_scores_gemma":[0.9937313,0.005638921,0.0001080596,0.0001040912,0.0001385903,0.000002259991,0.000003152907,0.00001972175,0.0002539038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.111354,"threshold_uncertainty_score":0.5238397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008799953768705956,"score_gpt":0.2348448483222513,"score_spread":0.2260448945535453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}