{"id":"W2137723066","doi":"10.1182/blood-2002-10-3280","title":"Safety and effectiveness of long-term therapy with the oral iron chelator deferiprone","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":319,"is_retracted":false,"has_abstract":true,"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Deferiprone; Medicine; Discontinuation; Neutropenia; Internal medicine; Chelation therapy; Thalassemia; Gastroenterology; Deferoxamine; Absolute neutrophil count; Regimen; Pediatrics; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001841734,0.0001889449,0.0006890568,0.0002088421,0.0002571314,0.000533691,0.0003928149,0.0007040395,0.000697441],"category_scores_gemma":[0.005716939,0.00007171424,0.0005662307,0.0002119581,0.0003162309,0.000388517,0.0002110748,0.0006207852,0.0001852823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003737727,"about_ca_system_score_gemma":0.0003795217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003609919,"about_ca_topic_score_gemma":0.0002945842,"domain_scores_codex":[0.9989628,0.0004661702,0.00009843412,0.00008391868,0.0003196326,0.00006905833],"domain_scores_gemma":[0.9949044,0.001933984,0.001896076,0.0002752279,0.0004194407,0.0005707588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.1493143,0.004478003,0.2810554,0.001081115,0.001565775,0.0009266775,0.0004852749,0.002712112,0.02338835,0.0003995337,0.001471073,0.5331223],"study_design_scores_gemma":[0.007427039,0.2359188,0.728774,0.0004399086,0.001511794,0.004014377,0.0002933321,0.003765899,0.008586138,0.0004909983,0.008715638,0.0000621653],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827365,0.01460926,0.0005016362,0.0002960113,0.00004290547,0.00003653957,0.0002682045,0.00002486565,0.001484195],"genre_scores_gemma":[0.9978117,0.001204492,0.0002156221,0.0001243045,0.0000784165,0.00003134682,0.0002488467,0.000002692411,0.0002826012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001841734,"threshold_uncertainty_score":0.009740174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006110720864404984,"score_gpt":0.2238983337599308,"score_spread":0.2177876128955258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}