{"id":"W2137795766","doi":"10.1007/s00109-005-0001-9","title":"The role of vesicular transport in ABCA1-dependent lipid efflux and its connection with NPC pathways","year":2005,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"ABCA1; NPC1; ATP-binding cassette transporter; Vesicular transport protein; ATP Binding Cassette Transporter 1; Endosome; Cell biology; Lipid-anchored protein; Biology; Cholesterol; Efflux; Transporter; Reverse cholesterol transport; Biochemistry; Lipoprotein; Chemistry; Vesicle; Autophagy; Membrane; Gene; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001583303,0.0003728569,0.002217046,0.000533726,0.00005202515,0.0000080942,0.0002752851,0.0002646136,0.00004302194],"category_scores_gemma":[0.0004141939,0.0001901933,0.0003029566,0.0005050313,0.0002071373,0.00006173535,0.00002912069,0.001214519,0.000002311966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002134299,"about_ca_system_score_gemma":0.0006225256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000298208,"about_ca_topic_score_gemma":0.0000294981,"domain_scores_codex":[0.9962791,0.0002684379,0.001343336,0.0002635866,0.001505434,0.00034016],"domain_scores_gemma":[0.9979097,0.0002080066,0.000867936,0.0003124445,0.0004203538,0.0002816076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004988542,0.0002925462,0.0001656774,0.006369927,0.0009443733,0.004619283,0.0004454704,0.0000128204,0.002745951,0.0001871834,0.00003805646,0.9836798],"study_design_scores_gemma":[0.007261901,0.004997008,0.0005880945,0.04802229,0.003526036,0.009205336,0.0007740816,0.00002569694,0.0007572622,0.00007031066,0.9244062,0.0003658203],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009721423,0.9881513,0.00006738184,0.0004341641,0.000102271,0.0009163344,0.000003422751,0.000005846411,0.000597831],"genre_scores_gemma":[0.03330582,0.9660223,0.00005456358,0.00005764211,0.0004006039,0.00001794062,0.00001400979,0.00006435713,0.00006272987],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.983314,"threshold_uncertainty_score":0.7755856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02336120114266352,"score_gpt":0.3097050484624733,"score_spread":0.2863438473198098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}