{"id":"W2137795766","doi":"10.1007/s00109-005-0001-9","title":"The role of vesicular transport in ABCA1-dependent lipid efflux and its connection with NPC pathways","year":2005,"lang":"en","type":"review","venue":"Journal of Molecular Medicine","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"ABCA1; NPC1; ATP-binding cassette transporter; Vesicular transport protein; ATP Binding Cassette Transporter 1; Endosome; Cell biology; Lipid-anchored protein; Biology; Cholesterol; Efflux; Transporter; Reverse cholesterol transport; Biochemistry; Lipoprotein; Chemistry; Vesicle; Autophagy; Membrane; Gene; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007732899,0.0009082331,0.001918509,0.001686361,0.0003544909,0.001591612,0.001266662,0.001663279,0.002173454],"category_scores_gemma":[0.0005038521,0.0003354923,0.0004746905,0.002187764,0.0008979308,0.002337854,0.0007874408,0.00164951,0.001767878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008449982,"about_ca_system_score_gemma":0.0009584868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007552552,"about_ca_topic_score_gemma":0.001118075,"domain_scores_codex":[0.9998598,0.00002622477,0.00002439317,0.00002933899,0.00004310311,0.0000170565],"domain_scores_gemma":[0.9997261,0.0001268939,0.0000393778,0.00001111022,0.00006888816,0.00002762242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003355486,0.00008357988,0.0003170763,0.01361722,0.0001545898,0.001203977,0.00009940076,0.0008804258,0.008246966,0.009374739,0.01896799,0.9467186],"study_design_scores_gemma":[0.00004170302,0.0001168618,0.001039203,0.001643259,0.0001804651,0.003121685,0.00009121182,0.0002601738,0.001870847,0.004023069,0.9875782,0.0000333201],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002452963,0.9983058,0.0002570727,0.0002643588,0.0001858006,0.000002974418,0.000009881359,0.000005762355,0.000723033],"genre_scores_gemma":[0.001137214,0.9977694,0.000301739,0.0001088643,0.0002179326,0.000004702198,0.00002280598,9.277278e-7,0.0004363749],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002173454,"threshold_uncertainty_score":0.007270932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02336120114266352,"score_gpt":0.3097050484624733,"score_spread":0.2863438473198098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}