{"id":"W2137850900","doi":"10.1016/j.bbrc.2006.05.190","title":"Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-δ","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Australian National University; Canadian Diabetes Association; Heart and Stroke Foundation of Canada","keywords":"Hepatocyte; Hyperinsulinemia; Insulin; Internal medicine; Endocrinology; Protein kinase C; Insulin receptor; Chemistry; Biology; Biochemistry; Insulin resistance; In vitro; Signal transduction; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002052406,0.0006019162,0.0005325528,0.0003839583,0.0003014317,0.0004025952,0.0003506229,0.000342182,0.00406967],"category_scores_gemma":[0.0002468257,0.0004223631,0.0005552052,0.0002895672,0.0004434046,0.0005438956,0.0004840479,0.00140424,0.0008718125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006495843,"about_ca_system_score_gemma":0.0004626501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378827,"about_ca_topic_score_gemma":0.00199093,"domain_scores_codex":[0.9997864,0.00003660519,0.00002255997,0.00004381318,0.00003669785,0.00007387113],"domain_scores_gemma":[0.9997883,0.0000338821,0.0000503534,0.00004397048,0.00003120199,0.00005225509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00605415,0.0001018304,0.0003575969,0.00007897489,0.00002277522,0.00009271986,0.00002903324,0.00002469559,0.9911843,0.0001945993,0.0001008065,0.001758481],"study_design_scores_gemma":[0.0001273721,0.0003001513,0.006931507,0.000006912863,0.00002348636,0.0001299494,0.00004294233,0.0002217797,0.9912336,0.00008179724,0.0008940358,0.000006386589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856986,0.004292671,0.005099958,0.0006442449,0.0002278735,0.00005769065,0.000899236,0.000237555,0.002842234],"genre_scores_gemma":[0.989917,0.001495413,0.001878714,0.0002003191,0.00003104209,0.00006019967,0.001108059,0.00005253915,0.005256732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00406967,"threshold_uncertainty_score":0.01361436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07122238875250753,"score_gpt":0.3712793822342285,"score_spread":0.3000569934817209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}