{"id":"W2137885127","doi":"10.1002/dvdy.22626","title":"Non‐canonical wnt signals antagonize and canonical wnt signals promote cell proliferation in early kidney development","year":2011,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Wnt signaling pathway; Xenopus; Biology; LRP6; Cell biology; Cell growth; Frizzled; Kidney development; Dishevelled; Internal medicine; Genetics; Signal transduction; Endocrinology; Embryonic stem cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001752853,0.0002757835,0.0002092201,0.0002805791,0.0001727235,0.0003784014,0.0001846243,0.0002046696,0.001568347],"category_scores_gemma":[0.00009235673,0.0002206772,0.0002083748,0.0001237782,0.0002539992,0.0002983476,0.0002619475,0.0004161867,0.0003358436],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002671064,"about_ca_system_score_gemma":0.0003365738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006315425,"about_ca_topic_score_gemma":0.002565282,"domain_scores_codex":[0.9998141,0.00002719096,0.00001659278,0.0000333452,0.00005819839,0.00005070619],"domain_scores_gemma":[0.9999008,0.00002064362,0.0000254859,0.0000114685,0.00001193027,0.00002962982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006452719,0.000006054555,0.0003658365,0.00003211326,0.000001843044,0.00006945492,0.00001028377,0.00002033201,0.9983652,0.0002681714,0.00001254769,0.0007836305],"study_design_scores_gemma":[0.000009765232,0.00008397282,0.006639358,0.00000380799,0.000008869748,0.0004133754,0.00002679883,0.0002286234,0.9902271,0.00004843566,0.002306619,0.00000324422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988875,0.004412028,0.00310532,0.00008092271,0.00002174147,0.00001911134,0.0001753225,0.00005759887,0.003252974],"genre_scores_gemma":[0.9909959,0.00185217,0.002433452,0.00003516862,0.00001130455,0.00001828742,0.0001584684,0.00001651726,0.004478619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001568347,"threshold_uncertainty_score":0.005246639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008318171781510363,"score_gpt":0.2080568872393807,"score_spread":0.1997387154578703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}