{"id":"W2137992445","doi":"10.1002/med.21321","title":"Lipopeptides from Bacillus and Paenibacillus spp.: A Gold Mine of Antibiotic Candidates","year":2014,"lang":"en","type":"review","venue":"Medicinal Research Reviews","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":471,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"U.S. Food and Drug Administration; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Lipopeptide; Antimicrobial; Daptomycin; Microbiology; Antibiotics; Bacillus (shape); Biology; Bacteria; Surfactin; Paenibacillus; Polymyxin; Bacillus subtilis; Vancomycin; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006747247,0.0007095857,0.006556088,0.0006624197,0.0001028493,0.00004615765,0.0005330262,0.0004935392,0.0008320686],"category_scores_gemma":[0.01036089,0.0003799835,0.0006526008,0.001076361,0.0009896071,0.00006354472,0.0003675925,0.001691668,0.0005566315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001836263,"about_ca_system_score_gemma":0.0005185512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001550076,"about_ca_topic_score_gemma":0.0001656198,"domain_scores_codex":[0.9934453,0.001545743,0.001872081,0.001118666,0.001193732,0.0008244268],"domain_scores_gemma":[0.9954904,0.001502584,0.0006624112,0.001273725,0.0004582964,0.000612638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005794397,0.00007120548,0.00001540123,0.07962395,0.0001911906,0.00007291971,0.00003443125,1.026046e-9,0.0005119148,0.00001339469,0.04375349,0.8756542],"study_design_scores_gemma":[0.0003698219,0.0006740144,0.00001754605,0.1237602,0.001408704,0.0001657052,0.00001498196,0.000001795004,0.000167115,0.00001344451,0.8731205,0.0002860891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002865146,0.9938573,0.000001638516,0.0006493148,0.0001898299,0.003290016,0.0001526001,0.00002071875,0.001552023],"genre_scores_gemma":[0.0002870297,0.9915407,0.0005641753,0.0001192311,0.001366289,0.00001227161,0.0002939326,0.0000740757,0.005742271],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8753681,"threshold_uncertainty_score":0.9998652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1420417147560837,"score_gpt":0.4133948455982349,"score_spread":0.2713531308421512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}