{"id":"W2137999973","doi":"10.1261/rna.033100.112","title":"Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Basic Energy Sciences; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Office of Science; National Institutes of Health; Eli Lilly and Company; U.S. Department of Energy","keywords":"Trans-activating crRNA; CRISPR; Biology; Genetics; RNA; CRISPR interference; Endonuclease; RNA silencing; Gene; DNA; Computational biology; Cas9; Nucleic acid; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006710061,0.00009837469,0.0001339156,0.00002597894,0.00001584959,0.000004265428,0.0000683643,0.00006824993,0.00002811338],"category_scores_gemma":[0.00006262089,0.00008876447,0.00004167092,0.00005929537,0.00004195196,0.000004243041,0.00006115191,0.00003373237,0.000001291256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002041176,"about_ca_system_score_gemma":0.00002647467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004447414,"about_ca_topic_score_gemma":0.00000579788,"domain_scores_codex":[0.999457,0.00000960653,0.0001527717,0.000125803,0.00008475697,0.0001700892],"domain_scores_gemma":[0.9996253,0.00001189491,0.00005563169,0.0001709548,0.00006951138,0.00006673545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003195672,0.00006438345,0.005021891,0.0002814383,0.00005139526,4.43851e-7,0.0003742166,0.00001778975,0.990505,0.00001280198,0.001863988,0.001774693],"study_design_scores_gemma":[0.0002049125,0.00008391101,0.01468466,0.00002890244,0.00003450445,0.00000877497,0.00009538018,0.00001856119,0.971254,0.000008177914,0.01347499,0.0001032461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826495,0.01458835,0.001176398,0.00001842918,0.00005870182,0.00008711709,0.00003367556,0.000005221224,0.001382616],"genre_scores_gemma":[0.9981143,0.0008085952,0.0006294869,0.00007170187,0.0001050962,0.000006569524,0.000006944224,0.000015705,0.0002415713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01925102,"threshold_uncertainty_score":0.361971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119678347638355,"score_gpt":0.2977407345515101,"score_spread":0.2865439510751265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}