{"id":"W2138025362","doi":"10.2337/diabetes.50.7.1553","title":"Improved Glucose Tolerance and Acinar Dysmorphogenesis by Targeted Expression of Transcription Factor PDX-1 to the Exocrine Pancreas","year":2001,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Pancreas; Internal medicine; Endocrinology; Biology; Exocrine gland; Acinar cell; Downregulation and upregulation; PDX1; Enteroendocrine cell; Islet; Endocrine system; Insulin; Hormone; Medicine; Secretion; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186456,0.0005781455,0.0004261644,0.0004122322,0.0001235003,0.0003779862,0.0003476892,0.0003693737,0.001316371],"category_scores_gemma":[0.0001245029,0.0002369549,0.0002920748,0.0002146095,0.0003415185,0.0003053906,0.0002759029,0.001111316,0.0002638866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188735,"about_ca_system_score_gemma":0.0001927609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002686864,"about_ca_topic_score_gemma":0.0003901238,"domain_scores_codex":[0.9998199,0.00002015303,0.00002767403,0.00005166823,0.0000403237,0.00004029752],"domain_scores_gemma":[0.9998073,0.00001736185,0.00008537306,0.00001951325,0.00001163987,0.00005879682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001806648,0.0000683066,0.0001660899,0.00002650587,0.000004609748,0.00005569277,0.00001249805,0.00004724192,0.998261,0.00007699101,0.00001666328,0.001083679],"study_design_scores_gemma":[0.00009605254,0.001359057,0.007731483,0.0000127311,0.00005536365,0.0004133117,0.00004949296,0.0008966252,0.9869066,0.00007961918,0.002392897,0.000006635429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960209,0.0008129947,0.002199254,0.00006118587,0.00003382971,0.00002938739,0.0002102313,0.00008933271,0.0005429789],"genre_scores_gemma":[0.9908932,0.001586649,0.002740647,0.00007660475,0.0000198384,0.00006668179,0.0004818975,0.00006012994,0.004074315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001316371,"threshold_uncertainty_score":0.00440371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082859733930253,"score_gpt":0.2251893386063207,"score_spread":0.2143607412670182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}