{"id":"W2138035164","doi":"10.1128/iai.01662-06","title":"Surface Expression of Toll-Like Receptor 9 Is Upregulated on Intestinal Epithelial Cells in Response to Pathogenic Bacterial DNA","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":149,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Fondation pour la Recherche Médicale; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Biology; Salmonella enterica; Microbiology; Secretion; TLR9; Toll-Like Receptor 9; Molecular biology; Gene expression; Salmonella; Gene; Bacteria; DNA methylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001559217,0.0001585067,0.0002317115,0.0002600818,0.0001453831,0.0000120643,0.00008350924,0.0002598011,0.0005596516],"category_scores_gemma":[0.0002497702,0.0001476889,0.00006176064,0.0002426719,0.00008753544,0.0001196264,0.00007761305,0.0003057717,0.0001989623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006813838,"about_ca_system_score_gemma":0.00004836405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003319583,"about_ca_topic_score_gemma":0.00002613673,"domain_scores_codex":[0.9982435,0.0008498552,0.0004424578,0.0001829067,0.0000429589,0.000238326],"domain_scores_gemma":[0.999108,0.0003742664,0.000143851,0.0002578124,0.00008830804,0.00002778056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0179607,0.0001613243,0.0008569146,0.00001046554,0.00001365582,0.000001237546,0.001229594,0.00001269642,0.9753935,0.000007629919,0.000324913,0.004027379],"study_design_scores_gemma":[0.001378031,0.0007743342,0.1151542,0.0001061405,0.00000660979,0.00001748089,0.00008871596,0.000002194449,0.8693355,0.000009999008,0.01299489,0.000131898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998198,0.00005110126,0.0001802153,0.00006521792,0.0010237,0.0002672181,0.00001878572,0.00004045967,0.0001553519],"genre_scores_gemma":[0.9991726,0.00004627199,0.0000580886,0.00007449477,0.00001812822,0.000004033511,0.00004093974,0.00001149145,0.000573941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1142973,"threshold_uncertainty_score":0.6127793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060407558607801,"score_gpt":0.2451258648460377,"score_spread":0.2345217892599597,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}