{"id":"W2138051343","doi":"10.1002/stem.2115","title":"In Vitro T-Cell Generation From Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination","year":2015,"lang":"en","type":"review","venue":"Stem Cells","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Biology; Induced pluripotent stem cell; Embryonic stem cell; Cell biology; Stem cell; Progenitor cell; Haematopoiesis; Cellular differentiation; In vitro; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004047498,0.0004052405,0.0006393498,0.0007627684,0.0001549901,0.0005826198,0.0004987486,0.0005668513,0.001847637],"category_scores_gemma":[0.0002457956,0.0001711652,0.0003151991,0.0007879842,0.000307424,0.0007098506,0.000351421,0.001043636,0.001310495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002711766,"about_ca_system_score_gemma":0.0004155185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003598267,"about_ca_topic_score_gemma":0.0005681761,"domain_scores_codex":[0.999873,0.00002129693,0.00001743082,0.00001935663,0.00005682242,0.00001207211],"domain_scores_gemma":[0.999911,0.00004027621,0.00001399262,0.000004080202,0.00002199795,0.000008687851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005832491,0.00007771401,0.0002980887,0.01602684,0.00006437049,0.0004223956,0.0001454107,0.0006043647,0.04473107,0.01474052,0.01386573,0.9089651],"study_design_scores_gemma":[0.00001438723,0.000123483,0.0005652441,0.001416036,0.00008206785,0.001413944,0.00007034814,0.0001577502,0.0187888,0.004001447,0.9733474,0.00001918467],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001136147,0.991735,0.002210683,0.0004589706,0.0002385177,0.00001650154,0.00006078308,0.00002644317,0.004116982],"genre_scores_gemma":[0.004761363,0.9908938,0.002100474,0.0003467966,0.0001277703,0.00002017077,0.00009630283,0.000004886786,0.001648336],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001847637,"threshold_uncertainty_score":0.006180942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1004801585316933,"score_gpt":0.3376234731705562,"score_spread":0.237143314638863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}