{"id":"W2138108723","doi":"10.1177/1040638715593368","title":"Progressive accumulation of the abnormal conformer of the prion protein and spongiform encephalopathy in the obex of nonsymptomatic and symptomatic Rocky Mountain elk ( <i>Cervus elaphus nelsoni</i> ) with chronic wasting disease","year":2015,"lang":"en","type":"article","venue":"Journal of Veterinary Diagnostic Investigation","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency","funders":"National Park Service","keywords":"Chronic wasting disease; Pathology; Transmissible spongiform encephalopathy; Biology; Anatomy; Bovine spongiform encephalopathy; Scrapie; Medicine; Disease; Prion protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093328,0.0002271625,0.0001594299,0.0006192924,0.0002170375,0.0002505981,0.0001411025,0.0002392749,0.0006301338],"category_scores_gemma":[0.0002132294,0.0001674698,0.0001060711,0.0001369659,0.0004274261,0.0002182656,0.0002430965,0.0001821443,0.000174446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002348934,"about_ca_system_score_gemma":0.0001219477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002433686,"about_ca_topic_score_gemma":0.006065175,"domain_scores_codex":[0.9999403,0.000005074067,0.000006416883,0.00001807803,0.00001500905,0.00001513388],"domain_scores_gemma":[0.9998549,0.00001375795,0.00006501235,0.000007819512,0.00002477922,0.00003376893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001383593,0.0001175173,0.3990554,0.0001256283,0.00008727433,0.01225942,0.001164814,0.0001556513,0.5772995,0.00007020264,0.0001002355,0.008180787],"study_design_scores_gemma":[0.0000115223,0.0004131307,0.977702,0.000009579619,0.00002433734,0.009546746,0.0004340065,0.0001371592,0.01143427,0.00002718431,0.0002537652,0.000006310046],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997376,0.00007978579,0.00004402065,0.000003365957,7.993612e-7,0.000002192481,0.00001833474,0.000002518594,0.0001113771],"genre_scores_gemma":[0.9991254,0.0001290182,0.0002832055,0.00001514369,0.000002491695,0.00000387363,0.00009021319,0.00000201479,0.0003486764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002433686,"threshold_uncertainty_score":0.004839003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02514178388711908,"score_gpt":0.2721301558021422,"score_spread":0.2469883719150232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}