{"id":"W2138317326","doi":"10.1042/bj20070585","title":"Co-planar 3,3′,4,4′,5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes","year":2007,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; David och Astrid Hageléns Stiftelse; European Commission","keywords":"Biphenyl; Aryl hydrocarbon receptor; Aryl; Chemistry; Hydrocarbon; Planar; Receptor; Gene; Stereochemistry; Biology; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007548687,0.0006442426,0.0006657121,0.0003109484,0.0002407629,0.00008385086,0.0006214539,0.0006551944,0.00009044293],"category_scores_gemma":[0.0001059,0.0005667288,0.0002979108,0.0003567261,0.0002299642,0.00002295427,0.00008000732,0.0007056543,0.00005198767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001446468,"about_ca_system_score_gemma":0.0001715636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003565289,"about_ca_topic_score_gemma":0.000002085295,"domain_scores_codex":[0.9964479,0.0001136289,0.001023724,0.0008243419,0.0006120778,0.0009783873],"domain_scores_gemma":[0.9977556,0.00005641014,0.0004741419,0.0004756786,0.0002128789,0.00102528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001825004,0.0004120805,0.009209164,0.00005260966,0.0005418082,0.00006532328,0.0000871369,0.000002941621,0.9796697,0.00002073592,0.006247285,0.001866168],"study_design_scores_gemma":[0.002180924,0.0015455,0.001907814,0.0001327022,0.0001077748,0.0003432994,0.0001312269,0.000006662625,0.9805269,0.00002937006,0.0124514,0.0006364618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936953,0.003478466,0.0005534432,0.0002169671,0.000649475,0.0008531522,0.0001243116,0.00003925426,0.0003896038],"genre_scores_gemma":[0.9934566,0.001397719,0.002860943,0.000221689,0.0008675841,0.00003670283,0.0008620769,0.0001004529,0.0001962059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007301351,"threshold_uncertainty_score":0.9996784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152240264421411,"score_gpt":0.2778298331086813,"score_spread":0.2626058066665402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}