{"id":"W2138317326","doi":"10.1042/bj20070585","title":"Co-planar 3,3′,4,4′,5-pentachlorinated biphenyl and non-co-planar 2,2′,4,6,6′-pentachlorinated biphenyl differentially induce recruitment of oestrogen receptor α to aryl hydrocarbon receptor target genes","year":2007,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; David och Astrid Hageléns Stiftelse; European Commission","keywords":"Biphenyl; Aryl hydrocarbon receptor; Aryl; Chemistry; Hydrocarbon; Planar; Receptor; Gene; Stereochemistry; Biology; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006867238,0.0002873249,0.0002235321,0.0002029306,0.0001206739,0.0002540263,0.0001395492,0.0001929681,0.001988647],"category_scores_gemma":[0.0001248095,0.000194275,0.0002261623,0.0003381828,0.0001953634,0.00009594674,0.0001625664,0.0002664898,0.0005058181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002986336,"about_ca_system_score_gemma":0.0002520653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001840015,"about_ca_topic_score_gemma":0.003200096,"domain_scores_codex":[0.9997689,0.00003609927,0.000009470554,0.00005479838,0.00006945978,0.00006124603],"domain_scores_gemma":[0.9999045,0.00001417557,0.00002808001,0.0000110269,0.00001986814,0.0000222457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002249057,0.00001416281,0.0003216692,0.00002536461,0.000007799713,0.00004492125,0.000006170304,0.00007666332,0.9986634,0.00002383528,0.00002653432,0.000564512],"study_design_scores_gemma":[0.00001608882,0.0004798028,0.01208226,0.000003198106,0.0000238929,0.0003403808,0.000087063,0.00028103,0.9840257,0.00003794585,0.002614154,0.000008554266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943242,0.001059105,0.00243576,0.00006359639,0.00003711289,0.00002257604,0.0004695443,0.00003615511,0.001551893],"genre_scores_gemma":[0.9902387,0.001295866,0.001843884,0.0001265579,0.000008752714,0.00003139691,0.001244666,0.00002215534,0.005188097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001988647,"threshold_uncertainty_score":0.006652713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0152240264421411,"score_gpt":0.2778298331086813,"score_spread":0.2626058066665402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}