{"id":"W2138337714","doi":"10.1128/jvi.06533-11","title":"Lack of Association between HLA Class II Alleles and <i>In Vitro</i> Replication Capacities of Recombinant Viruses Encoding HIV-1 Subtype C Gag-Protease from Chronically Infected Individuals","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; U.S. Public Health Service; National Institutes of Health","keywords":"Biology; Human leukocyte antigen; Allele; Virology; Recombinant DNA; HLA-B Antigens; Genetics; Viral replication; Lentivirus; In vitro; Group-specific antigen; Immunology; Human immunodeficiency virus (HIV); Virus; Gene; Viral disease; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003261589,0.0001989165,0.0001680745,0.0002691028,0.0001990358,0.0004119698,0.0001271487,0.0002969016,0.001963562],"category_scores_gemma":[0.001557878,0.000131752,0.0001265338,0.0001670371,0.00024145,0.0001414266,0.0001514161,0.0005139854,0.0002898832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092287,"about_ca_system_score_gemma":0.0001057754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005547093,"about_ca_topic_score_gemma":0.0003349367,"domain_scores_codex":[0.9996303,0.00009455575,0.00005452244,0.00009707458,0.00004979755,0.00007358736],"domain_scores_gemma":[0.9980955,0.0005459666,0.0006383623,0.000246108,0.0001425316,0.0003315588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001613868,0.0001438401,0.7232571,0.00003316615,0.0001361185,0.000428091,0.0002746067,0.0001594694,0.2682588,0.0002605202,0.0001683088,0.005266114],"study_design_scores_gemma":[0.00003928287,0.00146996,0.9631408,0.00001086394,0.00008850556,0.004695659,0.0003519697,0.0005491729,0.02846774,0.0002669516,0.0009047727,0.00001424616],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994693,0.00008373071,0.0001047825,0.000015695,0.000002197037,0.000001394334,0.00006242791,0.000002136198,0.0002584457],"genre_scores_gemma":[0.9996625,0.00002222791,0.00006793999,0.00001681795,0.000004964576,0.000001805474,0.00008517522,0.000002660737,0.0001358077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001963562,"threshold_uncertainty_score":0.00656873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0567559828960996,"score_gpt":0.2921462479733373,"score_spread":0.2353902650772377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}