{"id":"W2138350433","doi":"10.2174/09298673113209990183","title":"Gene Therapy, A Targeted Treatment for Diabetic Nephropathy","year":2013,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Birth, Development, and Health","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph's Hospital; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Genetic enhancement; Diabetic nephropathy; Medicine; Nephropathy; Diabetes mellitus; Gene; Computational biology; Bioinformatics; Internal medicine; Genetics; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002380338,0.0008836968,0.002825268,0.0001011086,0.0001367388,0.00002192333,0.0002398658,0.0004957155,0.0007116004],"category_scores_gemma":[0.00008786368,0.0005770429,0.0007402022,0.0002301402,0.00014469,0.00002812862,0.00003877266,0.0006295801,0.0001218775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008549429,"about_ca_system_score_gemma":0.002753025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008625501,"about_ca_topic_score_gemma":2.916456e-7,"domain_scores_codex":[0.996874,0.00004583173,0.001009758,0.0008109678,0.0004695513,0.0007898582],"domain_scores_gemma":[0.9977564,0.0001338313,0.00051384,0.0006545893,0.0001861441,0.0007552434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000369699,0.0004277997,0.00001593247,0.05582007,0.0003332401,0.00001839846,0.0001124027,4.1725e-9,0.0001417006,0.00001524502,0.006594469,0.9364838],"study_design_scores_gemma":[0.00269557,0.0004327005,0.000009622968,0.0156101,0.001435845,0.0001858684,0.00002598293,0.000005044265,0.000849607,0.000113014,0.9781555,0.0004811372],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002991084,0.9944336,0.00004060729,0.0001470912,0.0009107826,0.003270008,0.0001228405,0.0001140691,0.0006619378],"genre_scores_gemma":[0.00002465746,0.9906843,0.0003712263,0.000149344,0.002983163,0.002335957,0.0029637,0.0001250061,0.0003626505],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.971561,"threshold_uncertainty_score":0.9996681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1145073460195347,"score_gpt":0.3890576970840446,"score_spread":0.2745503510645099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}