{"id":"W2138417852","doi":"10.1111/epi.12185","title":"Design of innovative therapeutics for pharmacoresistant epilepsy: Challenges and needs","year":2013,"lang":"en","type":"review","venue":"Epilepsia","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Druggability; Computer science; Epilepsy; Medicine; Drug; Task (project management); Drug development; Neuroscience; Intensive care medicine; Medical physics; Pharmacology; Psychology; Engineering; Systems engineering; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001170723,0.0008491861,0.001675552,0.001410529,0.0003481843,0.001320939,0.0009216444,0.001644989,0.004016026],"category_scores_gemma":[0.0006848325,0.0002994481,0.0005730955,0.001403887,0.0007521176,0.003013592,0.0008594127,0.002547882,0.002532088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000708631,"about_ca_system_score_gemma":0.001519277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005500845,"about_ca_topic_score_gemma":0.001256353,"domain_scores_codex":[0.9996811,0.00006837833,0.00004217929,0.00004447066,0.0001244513,0.00003946647],"domain_scores_gemma":[0.9995921,0.0002060039,0.0000538748,0.00001569489,0.00009839464,0.00003386292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004905721,0.0001474798,0.00009117729,0.01506025,0.0000561373,0.000253024,0.0001234428,0.0006241902,0.004411147,0.01984376,0.01962773,0.9397125],"study_design_scores_gemma":[0.00002826751,0.0001298692,0.0003161378,0.003631046,0.00006491079,0.0009840481,0.0001539339,0.0001823732,0.0008486298,0.008983269,0.9846538,0.00002377478],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001910195,0.9968437,0.000460749,0.001012303,0.0001817484,0.000007225512,0.000009520028,0.00001058651,0.001283169],"genre_scores_gemma":[0.001022512,0.9966792,0.0008327954,0.0004772476,0.0001862683,0.00001396723,0.00001778236,0.000002392193,0.0007678659],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004016026,"threshold_uncertainty_score":0.01343489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2422401511908183,"score_gpt":0.4186209484556749,"score_spread":0.1763807972648566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}