{"id":"W2138440781","doi":"10.1128/mcb.00969-10","title":"p21-Activated Kinases 1 and 3 Control Brain Size through Coordinating Neuronal Complexity and Synaptic Properties","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children; Mental Health Research Canada","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cofilin; PAK1; Neuroscience; Synaptic plasticity; Dendritic spine; Synapse; Soma; Kinase; Synaptic fatigue; Long-term potentiation; Cell biology; Hippocampal formation; Actin cytoskeleton; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Cell; Cytoskeleton; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000217871,0.0002118374,0.0002663817,0.00005771092,0.0004230328,0.00008294435,0.0001924895,0.00011409,0.00003581506],"category_scores_gemma":[0.001268172,0.000171291,0.00003303757,0.0001596433,0.002422632,0.0001233134,0.0002463078,0.0005097373,0.000003803468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003642598,"about_ca_system_score_gemma":0.00003356457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003048266,"about_ca_topic_score_gemma":0.000003136338,"domain_scores_codex":[0.9979323,0.0005611676,0.0001831094,0.0007335159,0.0001226223,0.0004672668],"domain_scores_gemma":[0.998992,0.000596025,0.00006500313,0.0001718813,0.00003327228,0.000141775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001008549,0.00005091638,0.0009482151,0.00002291417,0.000006500965,0.0001715209,0.00005292887,5.609105e-7,0.9961234,0.002015543,0.00001149107,0.0004951185],"study_design_scores_gemma":[0.0009383403,0.0005232471,0.0007122508,0.000004629561,0.00001412001,0.0002490651,0.00001604248,0.0007781488,0.9947786,0.00104886,0.000754634,0.0001821077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961838,0.0001840381,0.0001829465,0.00273327,0.0001855811,0.0003454041,0.00001588259,0.00005319627,0.0001159298],"genre_scores_gemma":[0.9948907,0.00005249275,0.00004129522,0.004881167,0.00002957439,0.00002441209,7.564902e-7,0.00001921982,0.00006032296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002147898,"threshold_uncertainty_score":0.892629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04499411849762847,"score_gpt":0.3004960716169407,"score_spread":0.2555019531193122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}