{"id":"W2138449915","doi":"10.1371/journal.pgen.1005034","title":"The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors","year":2015,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; National Research Council Canada; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Neurogenesis; Dentate gyrus; Neural stem cell; Bromodomain; Cell biology; Stem cell; Epigenetics; Neuroscience; Genetics; Hippocampus; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001570959,0.000212478,0.0001363341,0.00001373891,0.0001954987,0.00008649922,0.0001940307,0.0001222674,0.000001962883],"category_scores_gemma":[0.00001936041,0.0001665143,0.0000458961,0.00007845834,0.00009380172,0.000005634575,0.0001275187,0.00009118222,0.000008680453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000314767,"about_ca_system_score_gemma":0.0001428539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004483424,"about_ca_topic_score_gemma":0.00004365831,"domain_scores_codex":[0.9987009,0.00008674103,0.0002741862,0.0003370632,0.0002912914,0.000309846],"domain_scores_gemma":[0.9992544,0.00002454997,0.00008276798,0.0003263072,0.0001369643,0.0001749918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009444662,0.00008741333,0.009062989,0.00001968026,0.0001225172,0.000003152077,0.0005269587,0.0002255816,0.977857,0.00001030016,0.000198374,0.01179158],"study_design_scores_gemma":[0.0005427279,0.0002032181,0.0004457432,0.000005320539,0.00003918969,0.000003458092,0.000213935,0.0003003366,0.9493084,0.00003935001,0.04868219,0.0002161379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925898,0.005795355,0.0007085167,0.0001272646,0.0002615648,0.0003385775,0.00001869299,0.00001456642,0.000145628],"genre_scores_gemma":[0.9965199,0.001484321,0.00120954,0.00008058005,0.0002352798,0.00003454554,0.00003064485,0.00004036279,0.0003648803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04848382,"threshold_uncertainty_score":0.6790255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03649582664507237,"score_gpt":0.2563769476917986,"score_spread":0.2198811210467262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}