{"id":"W2138516395","doi":"10.1158/1538-7445.am10-581","title":"Abstract 581: Development of RNA interference-based therapeutics for bladder cancer and hepatocellular carcinoma","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Survivin; Cancer research; Cancer; Small interfering RNA; Medicine; Apoptosis; RNA interference; Bladder cancer; Cancer cell; Liver cancer; Hepatocellular carcinoma; Cell culture; Transfection; Biology; Internal medicine; RNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002511281,0.0004921014,0.0003716445,0.0004223416,0.0001407463,0.0002255058,0.0003283663,0.0003222082,0.003082454],"category_scores_gemma":[0.00009109233,0.00015667,0.0003211706,0.0001773532,0.0001171804,0.0001515012,0.0001905105,0.0004830166,0.0009392049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003994445,"about_ca_system_score_gemma":0.0004738776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008206692,"about_ca_topic_score_gemma":0.0009687265,"domain_scores_codex":[0.9999092,0.00001354011,0.000007613623,0.000015551,0.00003333305,0.00002075943],"domain_scores_gemma":[0.9999497,0.000005400178,0.00001254369,0.000003109388,0.00001261015,0.00001670121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004822954,0.0003694133,0.000258835,0.0003566997,0.00003202616,0.0001545058,0.00003289152,0.0005000918,0.9476261,0.0008132113,0.001359026,0.04801483],"study_design_scores_gemma":[0.0006193931,0.007166192,0.004560871,0.00007142148,0.0001466054,0.0009012138,0.00002084212,0.003087501,0.9305903,0.0002871492,0.05252402,0.00002455163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8753355,0.04583886,0.02761774,0.001871705,0.0009067665,0.001156092,0.00192999,0.0009041914,0.04443917],"genre_scores_gemma":[0.9196565,0.02711454,0.01881202,0.0007471082,0.0001667441,0.0008616575,0.002816293,0.00007697533,0.02974811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003082454,"threshold_uncertainty_score":0.01031184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1116347214647418,"score_gpt":0.3891323330309027,"score_spread":0.2774976115661609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}