{"id":"W2138516897","doi":"10.1021/jp034246c","title":"Cisplatin-DNA Adducts by Vibrational Circular Dichroism Spectroscopy:  Structure and Isomerization of d(CCTG*G*TCC)·d(GGACCAGG) Intrastrand Cross-Linked by Cisplatin","year":2003,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Adduct; Isomerization; Histone octamer; Stereochemistry; Stacking; Circular dichroism; Vibrational circular dichroism; Guanine; Crystallography; Infrared spectroscopy; Photochemistry; DNA; Nucleotide; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227178,0.0003205472,0.0001492886,0.0002932037,0.0001372854,0.000222158,0.0001903104,0.0003081271,0.0007545875],"category_scores_gemma":[0.0002566264,0.0002174078,0.0001236651,0.0002599913,0.0002012915,0.0002241869,0.0001511749,0.0005137471,0.0001552403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002095044,"about_ca_system_score_gemma":0.0001391501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007516397,"about_ca_topic_score_gemma":0.0007737498,"domain_scores_codex":[0.9998778,0.00002312026,0.000007481267,0.00003729449,0.00003515136,0.00001905759],"domain_scores_gemma":[0.9998758,0.00002667664,0.00003563208,0.000008157101,0.0000292073,0.00002447246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002494678,0.000005751926,0.000126333,0.000007736048,0.000001761156,0.000008969695,0.00001351771,0.0000381217,0.999479,0.00001635981,0.000004571566,0.0002729578],"study_design_scores_gemma":[0.000004663231,0.0001998921,0.005956119,0.000002800185,0.00001022263,0.00009255808,0.00003546741,0.001398966,0.9918061,0.00004200216,0.0004444744,0.0000067629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950688,0.0007912751,0.003135358,0.00004473882,0.00001161658,0.00001446877,0.0001563079,0.00003141075,0.0007460125],"genre_scores_gemma":[0.9952601,0.0005322344,0.002588126,0.00004276915,0.000005453337,0.00001908773,0.0003421302,0.0000131774,0.001197056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007545875,"threshold_uncertainty_score":0.002524376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002671252479604398,"score_gpt":0.2216616295394412,"score_spread":0.2189903770598368,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}