{"id":"W2138517107","doi":"10.1186/1471-2156-11-44","title":"Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studies","year":2010,"lang":"en","type":"article","venue":"BMC Genetics","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Genotyping; Restriction fragment length polymorphism; Denaturing high performance liquid chromatography; Biology; Dot blot; Molecular biology; Genetics; Genotype; Restriction enzyme; Gene; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.06291132,0.002427721,0.001383262,0.00345729,0.0009676605,0.00185802,0.002265495,0.003173315,0.0008368918],"category_scores_gemma":[0.08672807,0.001421561,0.0009265632,0.002454621,0.003094862,0.001329188,0.00190744,0.001826821,0.0008767958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001046028,"about_ca_system_score_gemma":0.001093975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002126874,"about_ca_topic_score_gemma":0.002503991,"domain_scores_codex":[0.8659618,0.1000085,0.007616438,0.007495857,0.01703506,0.001882399],"domain_scores_gemma":[0.8690243,0.08830861,0.009618945,0.01272207,0.0187848,0.001541276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003127589,0.001356929,0.1154767,0.00148951,0.0007665617,0.0005935105,0.002939389,0.003034542,0.799316,0.002882066,0.0006985377,0.06831869],"study_design_scores_gemma":[0.0004665996,0.008080519,0.1679801,0.0004695462,0.00149973,0.003253033,0.00105316,0.03037686,0.7737682,0.001843666,0.01084604,0.0003625272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3575873,0.005591727,0.630113,0.0007343306,0.0005844876,0.002042137,0.0007515477,0.0004376303,0.002157828],"genre_scores_gemma":[0.375472,0.002265427,0.6157443,0.0004090925,0.0001443656,0.003262751,0.001157834,0.0001778964,0.001366416],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.06291132,"threshold_uncertainty_score":0.3327108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03594441676873542,"score_gpt":0.3487330736838583,"score_spread":0.3127886569151229,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}