{"id":"W2138539085","doi":"10.4049/jimmunol.180.9.5956","title":"Conversion of Tyrosine to the Inflammation-Associated Analog 3′-Nitrotyrosine at Either TCR- or MHC-Contact Positions Can Profoundly Affect Recognition of the MHC Class I-Restricted Epitope of Lymphocytic Choriomeningitis Virus Glycoprotein 33 by CD8 T Cells","year":2008,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"BC Cancer Agency","keywords":"Lymphocytic choriomeningitis; Epitope; MHC class I; Affect (linguistics); Tyrosine; T-cell receptor; Biology; Virology; Immunology; Major histocompatibility complex; T cell; Antigen; CD8; Immune system; Biochemistry; Psychology; Communication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001411454,0.0003815302,0.0001437669,0.00007476562,0.00009891239,0.0001747983,0.0001964252,0.0002439831,0.0009847081],"category_scores_gemma":[0.00009227767,0.0001432071,0.0001846368,0.00007064432,0.0002116889,0.0001531991,0.000154829,0.0005581859,0.0001596759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573984,"about_ca_system_score_gemma":0.0001314696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00044366,"about_ca_topic_score_gemma":0.0005786259,"domain_scores_codex":[0.9998592,0.00002561232,0.00001362988,0.00002868367,0.00002193161,0.00005097924],"domain_scores_gemma":[0.9999088,0.0000232459,0.00002751889,0.00001206393,0.000005031111,0.00002330072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001154483,0.00003358646,0.0000479555,0.00001047467,0.00000207851,0.00002314714,0.000009167589,0.00003763037,0.9995083,0.00002809944,0.000005017105,0.0001790954],"study_design_scores_gemma":[0.00002494463,0.001061182,0.001590074,0.000002631631,0.00001173375,0.0001062445,0.00001654339,0.0003505478,0.9962698,0.00002167221,0.0005416138,0.000002980089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999049,0.0001645708,0.0003878124,0.00001578537,0.00001048864,0.00001024975,0.00003436235,0.000009928138,0.0003178036],"genre_scores_gemma":[0.9986615,0.0001866129,0.000384243,0.00002501437,0.000004408637,0.00001744014,0.0001101469,0.000005886319,0.0006045962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009847081,"threshold_uncertainty_score":0.00329417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02115210569093352,"score_gpt":0.2637609353847526,"score_spread":0.2426088296938191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}