{"id":"W2138541587","doi":"10.1242/dev.129.2.361","title":"Hedgehog is required for murine yolk sac angiogenesis","year":2002,"lang":"en","type":"article","venue":"Development","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Hemangioblast; Biology; Yolk sac; Embryoid body; Vasculogenesis; Endoderm; Angiogenesis; Indian hedgehog; Cell biology; Embryonic stem cell; Mesoderm; Hedgehog; Internal medicine; Hedgehog signaling pathway; Endocrinology; Chorioallantoic membrane; Endothelial stem cell; Smoothened; Stem cell; Embryo; Genetics; Progenitor cell; Signal transduction; Adult stem cell; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001127458,0.000305514,0.0001880572,0.0003648623,0.0001379567,0.0002562272,0.0002154873,0.0002877347,0.001437268],"category_scores_gemma":[0.0001491973,0.0002586056,0.0002280746,0.0001157095,0.000188617,0.0001306665,0.0002284903,0.0004400919,0.0005952845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003419161,"about_ca_system_score_gemma":0.0001944796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00080715,"about_ca_topic_score_gemma":0.00108606,"domain_scores_codex":[0.9998137,0.00002401425,0.0000230042,0.00003405544,0.00006339729,0.00004175115],"domain_scores_gemma":[0.9997302,0.00003623241,0.00009396664,0.00002925562,0.00001926198,0.00009116823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007459972,0.000009814625,0.0001957607,0.00001331492,0.00000283527,0.00008840967,0.000008717071,0.00003969552,0.9987099,0.0001154681,0.00002878699,0.0007126132],"study_design_scores_gemma":[0.00003808664,0.000245722,0.0131074,0.00001024815,0.00002075353,0.000585867,0.00002836929,0.0008714275,0.979376,0.00008394759,0.005626807,0.00000546093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921018,0.001392082,0.002629346,0.00009923561,0.00002898939,0.00003747984,0.001113843,0.000162467,0.002434837],"genre_scores_gemma":[0.9904344,0.000518799,0.002661479,0.00004457473,0.00001073253,0.00004215198,0.001333624,0.00005924828,0.00489499],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001437268,"threshold_uncertainty_score":0.004808187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04640487693118031,"score_gpt":0.2543471349495854,"score_spread":0.2079422580184051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}