{"id":"W2138541587","doi":"10.1242/dev.129.2.361","title":"Hedgehog is required for murine yolk sac angiogenesis","year":2002,"lang":"en","type":"article","venue":"Development","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Hemangioblast; Biology; Yolk sac; Embryoid body; Vasculogenesis; Endoderm; Angiogenesis; Indian hedgehog; Cell biology; Embryonic stem cell; Mesoderm; Hedgehog; Internal medicine; Hedgehog signaling pathway; Endocrinology; Chorioallantoic membrane; Endothelial stem cell; Smoothened; Stem cell; Embryo; Genetics; Progenitor cell; Signal transduction; Adult stem cell; In vitro; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001382298,0.000178367,0.0001590695,0.00004507165,0.0001626802,0.00001499221,0.0001613674,0.00009571969,0.00008015362],"category_scores_gemma":[0.00006202442,0.0001731594,0.00009565737,0.00008125054,0.00003709781,0.000001908999,0.0001132503,0.00002357664,0.00009226225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002884582,"about_ca_system_score_gemma":0.00003919305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000152588,"about_ca_topic_score_gemma":0.000006862029,"domain_scores_codex":[0.998919,0.00001472841,0.0002440592,0.0003834586,0.0001229957,0.0003157237],"domain_scores_gemma":[0.9994993,0.00001129507,0.00005538329,0.0002542331,0.0001032114,0.00007657771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000719742,0.0002217892,0.004210952,0.0001197385,0.0005794434,0.000009791039,0.002243008,0.00001735287,0.7778303,0.00003862722,0.1520437,0.06261335],"study_design_scores_gemma":[0.0003590503,0.00006188665,0.001656895,0.0000104834,0.000009987326,0.000003204257,0.00003957115,0.00001871331,0.5073382,0.000008662926,0.4903021,0.0001912914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877394,0.003968779,0.005024219,0.0007175139,0.0003191711,0.0004456729,0.00004923197,0.00004999687,0.001686008],"genre_scores_gemma":[0.9676246,0.0002225641,0.01953437,0.00116468,0.000294526,0.0002347293,0.0001057629,0.00004735987,0.01077142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3382584,"threshold_uncertainty_score":0.7061234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04640487693118031,"score_gpt":0.2543471349495854,"score_spread":0.2079422580184051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}