{"id":"W2138543359","doi":"10.1128/jvi.76.12.5882-5892.2002","title":"Development and Characterization of Bovine × Human Hybrid Cell Lines That Efficiently Support the Replication of both Wild-Type Bovine and Human Adenoviruses and Those with E1 Deleted","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; McMaster University","keywords":"Biology; Cell culture; HEK 293 cells; Transfection; Plasmid; Gene; Somatic cell; Viral replication; Virology; Molecular biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007027642,0.0002886995,0.0004424247,0.0004606342,0.0003413495,0.0006014165,0.0003798427,0.0002863486,0.002603772],"category_scores_gemma":[0.0005272138,0.0002780272,0.0003289275,0.0005378033,0.0001915958,0.0002507991,0.0003285226,0.0006111602,0.002005942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003285921,"about_ca_system_score_gemma":0.0002547865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002458777,"about_ca_topic_score_gemma":0.003145424,"domain_scores_codex":[0.9995047,0.00008495816,0.00007845111,0.0001027418,0.0001374839,0.0000917127],"domain_scores_gemma":[0.9995238,0.0001374532,0.00005184075,0.00009641676,0.000121814,0.00006881421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001786393,0.0001040344,0.000780691,0.00007711525,0.00001317394,0.0001081516,0.0001410481,0.00009800724,0.9933888,0.0004435032,0.0003550012,0.004311887],"study_design_scores_gemma":[0.0001081335,0.001042724,0.01579523,0.00003206418,0.0000931697,0.002168127,0.0002437377,0.002132367,0.920121,0.000154337,0.05806645,0.00004273095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.901659,0.008844562,0.06591278,0.0004111501,0.0002376867,0.00114188,0.01082191,0.0005165094,0.01045456],"genre_scores_gemma":[0.8903452,0.003942318,0.06856929,0.000224027,0.00007918983,0.0006151665,0.02397401,0.0002092783,0.01204152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002603772,"threshold_uncertainty_score":0.008710504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02996466126161761,"score_gpt":0.2869775505841315,"score_spread":0.2570128893225139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}