{"id":"W2138543359","doi":"10.1128/jvi.76.12.5882-5892.2002","title":"Development and Characterization of Bovine × Human Hybrid Cell Lines That Efficiently Support the Replication of both Wild-Type Bovine and Human Adenoviruses and Those with E1 Deleted","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; McMaster University","keywords":"Biology; Cell culture; HEK 293 cells; Transfection; Plasmid; Gene; Somatic cell; Viral replication; Virology; Molecular biology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004131286,0.0001043949,0.0002016069,0.00008849728,0.00008237565,0.0000101254,0.0001128333,0.00006306627,0.00001820958],"category_scores_gemma":[0.00002012888,0.00007098222,0.00001897339,0.00006035646,0.0002180993,0.000008558817,0.00006041572,0.00009584222,1.768432e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000581931,"about_ca_system_score_gemma":0.00003959279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004129569,"about_ca_topic_score_gemma":0.0000284476,"domain_scores_codex":[0.9991521,0.00008824375,0.0003235363,0.0001762102,0.0001375279,0.0001224193],"domain_scores_gemma":[0.999136,0.00001545185,0.0004322973,0.0002139031,0.0001514195,0.00005091195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001111753,0.0001134043,0.01303621,0.00003042572,0.00005686662,0.000003768948,0.0001814302,0.000003128139,0.9833125,0.000003908905,0.00005430273,0.002092312],"study_design_scores_gemma":[0.001049575,0.008957717,0.04717904,0.00001826752,0.00003713338,0.0001480225,0.00003081845,0.00003025893,0.9401588,0.000004810363,0.002303148,0.00008245146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985136,0.001040057,0.00008530495,0.0001962483,0.00001337948,0.0001260551,0.000005931905,0.000001689382,0.00001770789],"genre_scores_gemma":[0.9985598,0.0009349259,0.000178238,0.0001442096,0.00005126133,0.000002155376,0.00002643299,0.00001362117,0.00008929415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04315373,"threshold_uncertainty_score":0.2894571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02996466126161761,"score_gpt":0.2869775505841315,"score_spread":0.2570128893225139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}