{"id":"W2138581078","doi":"10.3109/07357907.2014.889706","title":"Presurgical Trial of Metformin in Overweight and Obese Patients with Newly Diagnosed Breast Cancer","year":2014,"lang":"en","type":"article","venue":"Cancer Investigation","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Medicine; Metformin; Overweight; Breast cancer; Cancer; Obesity; Internal medicine; Oncology; Clinical trial; Gynecology; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001447553,0.0001224981,0.0001910197,0.00003928883,0.00002618946,0.00001138144,0.00007482895,0.0001015995,0.00003426054],"category_scores_gemma":[0.0000469031,0.00009800136,0.00002693633,0.0001075059,0.000134352,0.00001420801,0.00002703852,0.00005875141,3.572699e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002314362,"about_ca_system_score_gemma":0.0001297099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003958549,"about_ca_topic_score_gemma":0.0005645577,"domain_scores_codex":[0.9991436,0.0000731265,0.000208577,0.000259276,0.0001598361,0.0001556073],"domain_scores_gemma":[0.9994951,0.00001673233,0.0001341502,0.0001626436,0.00009874611,0.00009266724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008715397,0.0002309012,0.5370706,0.0002142193,0.0001095234,6.8145e-7,0.0004459117,0.0006213472,0.009677865,0.0004274088,0.001713607,0.4407725],"study_design_scores_gemma":[0.09745213,0.001012925,0.7229793,0.0004028222,0.0001561133,0.000001145822,0.00003980391,0.0005686431,0.09732711,0.00108896,0.07825837,0.0007126806],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853454,0.01392593,0.00002457065,0.00003730683,0.0001898613,0.0003134931,0.0000729754,0.000004086172,0.00008636284],"genre_scores_gemma":[0.9916807,0.007220368,0.0001254563,0.0002794869,0.0003518499,0.0002155064,0.00008060024,0.00001569538,0.00003030855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4400599,"threshold_uncertainty_score":0.399638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007382633654831579,"score_gpt":0.2316883924968264,"score_spread":0.2243057588419948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}