{"id":"W2138589646","doi":"10.1039/c3fo60588d","title":"Blueberry polyphenols prevent cardiomyocyte death by preventing calpain activation and oxidative stress","year":2014,"lang":"en","type":"article","venue":"Food & Function","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Agriculture and Agri-Food Canada; St. Boniface Hospital","funders":"Agriculture and Agri-Food Canada; Manitoba Health Research Council","keywords":"Calpain; Oxidative stress; Catalase; Superoxide dismutase; Chemistry; Programmed cell death; Apoptosis; Muscle hypertrophy; Polyphenol; Pharmacology; Biochemistry; Antioxidant; Biology; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000882328,0.0003577707,0.0002776863,0.0001876616,0.000153645,0.0001562364,0.0001668394,0.0002459942,0.0009247917],"category_scores_gemma":[0.00009640972,0.00008643501,0.0001899317,0.00007091951,0.0001275974,0.0002417257,0.0001308075,0.0003344523,0.0001182871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000850489,"about_ca_system_score_gemma":0.0001173797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002747345,"about_ca_topic_score_gemma":0.0009188736,"domain_scores_codex":[0.9999559,0.000008847494,0.000003499123,0.000008852322,0.00001009264,0.00001287363],"domain_scores_gemma":[0.9999292,0.00001079177,0.00002190641,0.000008021688,0.00001314842,0.00001693498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003840789,0.0001174833,0.0003743591,0.0001005911,0.00001800667,0.00004654362,0.00001387222,0.00002459359,0.9954224,0.00002478631,0.00002661378,0.003446579],"study_design_scores_gemma":[0.00008283139,0.002981865,0.02613736,0.00002066829,0.00006940949,0.0002998983,0.00004726518,0.0002542802,0.9681535,0.0000660915,0.001881736,0.000005048673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948105,0.003761776,0.0007231883,0.00006980306,0.00002161534,0.00001531873,0.00005822833,0.00002299603,0.0005167233],"genre_scores_gemma":[0.9943422,0.002774729,0.001214674,0.00008402028,0.00002504012,0.00001750469,0.0001936519,0.000008697517,0.001339596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009247917,"threshold_uncertainty_score":0.003093779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00670417696084709,"score_gpt":0.2101647378113513,"score_spread":0.2034605608505042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}