{"id":"W2138589646","doi":"10.1039/c3fo60588d","title":"Blueberry polyphenols prevent cardiomyocyte death by preventing calpain activation and oxidative stress","year":2014,"lang":"en","type":"article","venue":"Food & Function","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Agriculture and Agri-Food Canada; St. Boniface Hospital","funders":"Agriculture and Agri-Food Canada; Manitoba Health Research Council","keywords":"Calpain; Oxidative stress; Catalase; Superoxide dismutase; Chemistry; Programmed cell death; Apoptosis; Muscle hypertrophy; Polyphenol; Pharmacology; Biochemistry; Antioxidant; Biology; Endocrinology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832859,0.0001525338,0.0001158212,0.00004580046,0.0001567572,0.00003713837,0.00004369129,0.0001540561,0.00002221552],"category_scores_gemma":[0.00009176646,0.0001470662,0.00006688414,0.00007376391,0.00002966503,0.00001632869,0.00005134442,0.00008396242,0.000004157736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002859532,"about_ca_system_score_gemma":0.00002097597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002931901,"about_ca_topic_score_gemma":0.00001590755,"domain_scores_codex":[0.9989676,0.0001770002,0.0001770933,0.000360711,0.0001481031,0.0001695111],"domain_scores_gemma":[0.9995186,0.00001798811,0.0001242445,0.000197806,0.00006728472,0.00007406672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001261308,0.0001419334,0.004196931,0.00006158776,0.00024073,9.604461e-8,0.00007795639,0.0003004568,0.9472081,0.0003621187,0.001769727,0.04437904],"study_design_scores_gemma":[0.001575053,0.008277712,0.02656353,0.00009505714,0.0001402284,0.00001022634,0.0002439164,0.00142789,0.8361,0.000581796,0.1244318,0.0005528057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8970873,0.0003012436,0.1012522,0.0001007747,0.0002188734,0.0003646919,0.00001672782,0.00003666804,0.0006215991],"genre_scores_gemma":[0.9978982,0.0000213726,0.0001564069,0.0001424893,0.0004010766,0.00006189237,0.0005014838,0.0000210922,0.0007960038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.122662,"threshold_uncertainty_score":0.5997184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00670417696084709,"score_gpt":0.2101647378113513,"score_spread":0.2034605608505042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}