{"id":"W2138613983","doi":"10.1096/fj.08-110213","title":"utocrine role of endogenous interleukin‐18 on inflammatory cytokine generation by human neutrophils","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Innate immune system; Cell biology; Cytokine; MAPK/ERK pathway; Secretion; p38 mitogen-activated protein kinases; Lipopolysaccharide; Biology; Proinflammatory cytokine; Signal transduction; Acquired immune system; Immunology; Interleukin; Inflammation; Immune system; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001579192,0.0001314977,0.000126213,0.00004464942,0.0003022783,0.00001484671,0.000245052,0.0000627089,0.00007006538],"category_scores_gemma":[0.00001743901,0.00009646601,0.0001184353,0.00004116509,0.0001108908,0.000006320876,0.00004954967,0.0001859479,0.00001036079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001579039,"about_ca_system_score_gemma":0.00005361393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001070375,"about_ca_topic_score_gemma":0.000004888288,"domain_scores_codex":[0.9991567,0.00008536199,0.0002969799,0.0001194814,0.0001462414,0.000195196],"domain_scores_gemma":[0.999421,0.000004560838,0.0001812413,0.0002621047,0.00008648243,0.00004462992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000872571,0.00005756424,0.0005702708,0.000002551346,0.00006285174,0.0000110482,0.0001682654,0.0001752761,0.9952332,0.00004843874,0.002943939,0.0006392882],"study_design_scores_gemma":[0.0006511884,0.0005933243,0.0004577352,0.000007605245,0.00001428809,0.0004050802,0.0001062499,0.0000219689,0.9886205,0.00004172997,0.008972235,0.0001081453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966908,0.00100416,0.00005196182,0.00006978713,0.0001009816,0.00009871737,0.00001141247,0.000004851567,0.001967295],"genre_scores_gemma":[0.9983959,0.0004864786,0.00001611147,0.0001891195,0.000447768,0.000005516661,0.00008410085,0.00001881938,0.0003562378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0066128,"threshold_uncertainty_score":0.393377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.019350273062564,"score_gpt":0.2265567912528363,"score_spread":0.2072065181902723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}