{"id":"W2138631371","doi":"10.1081/dmr-120005657","title":"<i>N</i>-OXIDATION OF AROMATIC AMINES BY INTRACELLULAR OXIDASES","year":2002,"lang":"en","type":"article","venue":"Drug Metabolism Reviews","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Aromatic amine; Peroxidase; Reactive oxygen species; Biochemistry; Oxidative phosphorylation; Amine gas treating; DNA damage; CYP1A2; Glutathione; Oxidative stress; DNA; Enzyme; Cytochrome P450; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002891796,0.0001796258,0.0004031528,0.0000379206,0.00004158158,0.00001566867,0.0001764309,0.00006347786,0.0001481627],"category_scores_gemma":[0.00008677264,0.0001506984,0.0001943606,0.000133174,0.00005185765,0.000006049681,0.00005550761,0.00005151947,0.00004484785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004595979,"about_ca_system_score_gemma":0.000005942657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002160172,"about_ca_topic_score_gemma":0.000007784046,"domain_scores_codex":[0.9987755,0.0001553032,0.0004785654,0.0002664111,0.0001460915,0.0001780602],"domain_scores_gemma":[0.9991871,0.000009924382,0.0002476172,0.0004491622,0.0000392422,0.00006701867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000276449,0.000107381,0.00008482463,0.00008430958,0.00002252361,4.399457e-7,0.00004919357,0.000001843767,0.9352224,0.00003279781,0.04658697,0.01780448],"study_design_scores_gemma":[0.0001429061,0.00001502352,0.0001658381,0.00001784476,0.00004363552,0.000002732666,0.00001444092,0.00001884354,0.5104187,0.00001567749,0.4890423,0.0001020949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7998587,0.198003,0.0009160485,0.000153355,0.0001260729,0.0003979724,0.00002613036,0.000007125464,0.00051154],"genre_scores_gemma":[0.9363508,0.05839048,0.001952981,0.000432252,0.0002216529,0.0000772606,0.0002069863,0.00002451592,0.002343042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4424553,"threshold_uncertainty_score":0.6145302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01447312139975641,"score_gpt":0.2397358572831429,"score_spread":0.2252627358833865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}