{"id":"W2138632232","doi":"10.1186/1742-6405-8-20","title":"T cell Activation does not drive CD4 decline in longitudinally followed HIV-infected Elite Controllers","year":2011,"lang":"en","type":"article","venue":"AIDS Research and Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Maple Leaf Medical Clinic; University of Toronto; Royal Victoria Hospital; Clinique Paro Excellence; Centre Hospitalier de l’Université de Montréal; McGill University; McGill University Health Centre","funders":"Styrelsen för Internationellt Utvecklingssamarbete","keywords":"CD38; CD8; Immune system; Medicine; Human immunodeficiency virus (HIV); Viral load; Immunology; Antiretroviral therapy; Internal medicine; HLA-DR; Biology; Antigen; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00086622,0.0001784154,0.000291858,0.0004360175,0.0002479145,0.00003628859,0.0002098901,0.0001835692,0.0009696995],"category_scores_gemma":[0.0001193387,0.0001150403,0.00006800322,0.0003499822,0.0003673948,0.0001559296,0.00009936013,0.0005145637,0.0004927851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005979266,"about_ca_system_score_gemma":0.0001226694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001071649,"about_ca_topic_score_gemma":0.0002435929,"domain_scores_codex":[0.9978711,0.0005950034,0.000239287,0.0003977795,0.0001399638,0.0007568531],"domain_scores_gemma":[0.9988538,0.0005111503,0.00004478859,0.0002768459,0.0002236708,0.00008975641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01124847,0.001759677,0.2363256,0.00001705121,0.0005475495,0.00009544846,0.0017995,3.190888e-7,0.6829652,0.000825797,0.001071885,0.06334349],"study_design_scores_gemma":[0.02482377,0.005143692,0.3615621,0.00005429209,0.000008755705,0.000007397799,0.0005196149,0.000005301884,0.5890183,0.002432955,0.01612674,0.0002971426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916368,0.002178513,0.00006125335,0.0004827995,0.00005828317,0.0007480723,0.0000543121,0.00003615726,0.004743828],"genre_scores_gemma":[0.9891404,0.005830132,0.0001089266,0.00009432251,0.0000211416,0.0001509546,0.00015733,0.00001777958,0.004479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1252365,"threshold_uncertainty_score":0.9999436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04908958926792124,"score_gpt":0.3183610957200065,"score_spread":0.2692715064520853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}