{"id":"W2138666899","doi":"10.1158/1078-0432.ccr-11-2956","title":"Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial","year":2012,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; University of British Columbia; McMaster University; BC Cancer Agency","funders":"National Cancer Institute","keywords":"Epirubicin; Medicine; Internal medicine; Anthracycline; Cyclophosphamide; Oncology; Breast cancer; Fluorouracil; Chemotherapy; Proportional hazards model; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008909713,0.0001323597,0.000534403,0.0001053297,0.0000970613,0.00001216017,0.0003428832,0.0001503644,0.00004487352],"category_scores_gemma":[0.004652521,0.00008403973,0.0001914474,0.0003756231,0.0007313381,0.000007505494,0.0002286268,0.0003052638,0.00001961637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006158622,"about_ca_system_score_gemma":0.0003158981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000618586,"about_ca_topic_score_gemma":0.0005266551,"domain_scores_codex":[0.9958647,0.002258613,0.0006284591,0.0003407183,0.0004467123,0.0004607939],"domain_scores_gemma":[0.9974352,0.001573705,0.0001040522,0.000478248,0.0002965549,0.0001122162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9594273,0.0006829045,0.02665108,0.00002552176,0.0001235001,0.000004251262,0.0002652646,0.00001272596,0.001926951,0.0003966664,0.001539468,0.008944362],"study_design_scores_gemma":[0.6552073,0.001436497,0.2858099,0.000147321,0.0001126788,0.000005496128,0.0005260675,0.000005482326,0.02372743,0.0002998524,0.03241305,0.0003089028],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889839,0.006004661,0.0000508126,0.002727603,0.0005687876,0.001401792,0.00002998938,0.000004335878,0.000228084],"genre_scores_gemma":[0.9948398,0.002641484,0.00007260143,0.0002595019,0.001338126,0.0007150666,0.00002505797,0.00001334579,0.00009502366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.30422,"threshold_uncertainty_score":0.5569838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.149470228483138,"score_gpt":0.5124521046489711,"score_spread":0.3629818761658331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}