{"id":"W2138711760","doi":"10.1186/gb-2010-11-s1-o9","title":"Candidate genes and biological processes in de novo CNVs from autistic individuals","year":2010,"lang":"en","type":"article","venue":"Genome Biology","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Autism; Copy-number variation; Genetics; Gene; Candidate gene; Autistic traits; Psychology; Biology; Computational biology; Developmental psychology; Genome; Autism spectrum disorder","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001422063,0.000135387,0.0001595292,0.0000470526,0.00006644898,0.00001956861,0.000168524,0.0002828588,0.0001097621],"category_scores_gemma":[0.0001054546,0.0001148275,0.00002113115,0.00006082561,0.0001609104,0.000002635323,0.0001484745,0.0001107995,0.00001012774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008363837,"about_ca_system_score_gemma":0.0001365471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002101766,"about_ca_topic_score_gemma":0.001244097,"domain_scores_codex":[0.9991108,0.00005682031,0.0001873886,0.0003302026,0.00002373646,0.0002910466],"domain_scores_gemma":[0.9996516,0.00002728116,0.0000559001,0.0001735072,0.00003171477,0.00006002063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001337277,0.00002360424,0.3526457,0.000007078014,0.00002087802,0.000002995543,0.0001468709,0.000002895054,0.6462089,0.0004036126,0.000007754571,0.0005163222],"study_design_scores_gemma":[0.001125595,0.0004325707,0.8526678,0.000006185147,0.00002418292,0.0001478171,0.0002974238,0.000008783984,0.04134732,0.005596148,0.09782127,0.0005249048],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973074,0.001570758,0.0001844786,0.0001440859,0.0001183591,0.0001022859,0.0003680852,0.00001070412,0.0001938815],"genre_scores_gemma":[0.9965574,0.000527396,0.00171906,0.0002317273,0.000255215,0.0000379866,0.0005903252,0.000009446396,0.00007142789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6048616,"threshold_uncertainty_score":0.4682531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009830314355040271,"score_gpt":0.2337695103271699,"score_spread":0.2239391959721296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}