{"id":"W2138769482","doi":"10.1093/jac/dkq129","title":"Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates","year":2010,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Virology; Biology; Frameshift mutation; Mutation; Resistance mutation; Drug resistance; Reverse transcriptase; Protease; Group-specific antigen; Virus; Gene; Microbiology; Genetics; Polymerase chain reaction; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369898,0.0001625908,0.0001576478,0.0003252618,0.0002126899,0.0002837924,0.0001378534,0.0003207264,0.0006438911],"category_scores_gemma":[0.0006132258,0.0000907142,0.0001710197,0.0003227117,0.0001758336,0.0000939805,0.00009778568,0.0002322216,0.0001618539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002487769,"about_ca_system_score_gemma":0.0001806693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002104132,"about_ca_topic_score_gemma":0.001630751,"domain_scores_codex":[0.999836,0.00003312488,0.00001779715,0.00004860446,0.0000284497,0.00003600954],"domain_scores_gemma":[0.9997675,0.00006165264,0.000077227,0.00002008088,0.00003293222,0.00004063953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006252332,0.00007512818,0.9158299,0.0000376223,0.00006623214,0.0008968377,0.0004274051,0.0002226378,0.07518164,0.00004553809,0.00007689968,0.006514967],"study_design_scores_gemma":[0.00001486755,0.0003674404,0.9890827,0.000005981216,0.00002670129,0.003199029,0.0002819558,0.0002963519,0.006369331,0.00002052095,0.0003303529,0.000004771653],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997639,0.00006567493,0.00003067526,0.000004888002,6.560732e-7,0.000002587338,0.00005690938,9.422664e-7,0.00007369595],"genre_scores_gemma":[0.9996495,0.00003880516,0.00008890548,0.00001019204,0.000002110324,0.000002494714,0.0001460174,0.000001340906,0.00006065979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002104132,"threshold_uncertainty_score":0.00418371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006052799596855793,"score_gpt":0.2340288525820025,"score_spread":0.2279760529851467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}