{"id":"W2138801414","doi":"10.1186/rr73","title":"Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gels","year":2001,"lang":"en","type":"article","venue":"Respiratory Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Matrix metalloproteinase; Zymography; Neutrophil elastase; Extracellular matrix; Elastase; Fibroblast; Chemistry; Gelatinase; Type I collagen; Cell biology; Gelatinases; Cell culture; Molecular biology; Immunology; Biochemistry; Biology; Inflammation; Enzyme; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005415523,0.0003575619,0.0002048845,0.0002199248,0.0001596698,0.00054983,0.0001932812,0.0003046786,0.0007478363],"category_scores_gemma":[0.0002698774,0.000167942,0.0002269321,0.0001404413,0.0002422231,0.0003124239,0.0003067004,0.0003232281,0.0002833807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002211309,"about_ca_system_score_gemma":0.0002220758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003216042,"about_ca_topic_score_gemma":0.0009990223,"domain_scores_codex":[0.99967,0.0001029031,0.00003254279,0.00004501518,0.00009856216,0.00005095229],"domain_scores_gemma":[0.9996616,0.0001386945,0.00007166066,0.00002564301,0.00004288584,0.00005953469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001704901,0.00003454697,0.0007442684,0.0001025999,0.00001083177,0.0002069703,0.00004388564,0.00006267926,0.9968996,0.00007929593,0.00003219104,0.001612662],"study_design_scores_gemma":[0.00005639415,0.0006851331,0.02224442,0.00004804265,0.00005949148,0.00151888,0.0001295055,0.002514638,0.9687942,0.0002561735,0.003676912,0.00001626162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707311,0.01410353,0.01331003,0.0001867765,0.0000512338,0.00007673455,0.000153701,0.00003733703,0.001349487],"genre_scores_gemma":[0.985414,0.003114012,0.01014948,0.00006412944,0.00002294334,0.00007148883,0.0001170467,0.000004081335,0.001042751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007478363,"threshold_uncertainty_score":0.002864063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05601128836176095,"score_gpt":0.3642598697588068,"score_spread":0.3082485813970458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}