{"id":"W2138847465","doi":"10.1186/ar325","title":"Articular cartilage and changes in arthritis: matrix degradation.","year":2001,"lang":"en","type":"review","venue":"Arthritis Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":172,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University; Shriners Hospitals for Children - Canada","funders":"","keywords":"Aggrecan; Proteases; Matrix metalloproteinase; Aggrecanase; Collagenase; Type II collagen; Chemistry; Cleavage (geology); Cartilage; Metalloproteinase; Proteolysis; Cell biology; Proteoglycan; Biochemistry; Extracellular matrix; Enzyme; Articular cartilage; Biology; Osteoarthritis; Anatomy; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001056087,0.0002887853,0.0006575846,0.0003328626,0.0001442304,0.0001095922,0.0002380809,0.0004734005,0.00007762085],"category_scores_gemma":[0.0002393814,0.0002847397,0.0001305661,0.0004531654,0.0001532402,0.000008740723,0.0003391562,0.0004916545,0.00009201297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003737428,"about_ca_system_score_gemma":0.0002152328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005756683,"about_ca_topic_score_gemma":0.001175293,"domain_scores_codex":[0.9972521,0.0005662169,0.0003904297,0.0007091634,0.0003966466,0.00068544],"domain_scores_gemma":[0.9990727,0.00004116052,0.00007194089,0.0005142393,0.0001138326,0.0001861325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007938627,0.0000466957,0.000005633183,0.0007575864,0.00001802845,0.0002417422,0.00001208293,8.356896e-8,0.003878299,0.0002084291,0.001517735,0.9933057],"study_design_scores_gemma":[0.0004034494,0.0003001889,0.000001076939,0.006727428,0.000009672544,0.0002355105,0.00003519208,0.000001519875,0.0119474,0.000229602,0.9798065,0.0003024619],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001033667,0.9972597,0.00002527842,0.00007344765,0.00008038877,0.001002844,0.0000580876,0.00001330531,0.0004533197],"genre_scores_gemma":[0.00116397,0.9963067,0.0001378278,0.00002777649,0.0004183561,0.0006124761,0.0003193881,0.0000600341,0.000953538],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9930033,"threshold_uncertainty_score":0.9999605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05912504769372656,"score_gpt":0.3788142196036626,"score_spread":0.3196891719099361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}