{"id":"W2138925054","doi":"10.1186/1748-7161-6-26","title":"Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy","year":2011,"lang":"en","type":"article","venue":"Scoliosis","topic":"Birth, Development, and Health","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster University","keywords":"Exposome; Epigenetics; Medicine; Perspective (graphical); Scoliosis; Idiopathic scoliosis; Neurology; Bioinformatics; Neuroscience; Pathology; Physiology; Psychiatry; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005441707,0.0007170943,0.0007566311,0.001264188,0.0006970548,0.001649699,0.0005968183,0.001044586,0.001364876],"category_scores_gemma":[0.0004605482,0.0001482177,0.0005758557,0.0008777028,0.001617789,0.001962755,0.001231008,0.001628714,0.0001829862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008356546,"about_ca_system_score_gemma":0.00127355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001997956,"about_ca_topic_score_gemma":0.003886741,"domain_scores_codex":[0.9998004,0.00007010932,0.00001482678,0.00005059546,0.00003722238,0.00002693698],"domain_scores_gemma":[0.9997521,0.00009574142,0.0000490111,0.00001237666,0.00004875432,0.00004210532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005893856,0.0003012611,0.04400074,0.008184114,0.0007156503,0.00745151,0.007038168,0.002971812,0.04639937,0.3319953,0.02913442,0.5212183],"study_design_scores_gemma":[0.00004973534,0.00122994,0.1392067,0.004742361,0.00128085,0.01666695,0.01296106,0.007548953,0.008552111,0.3029963,0.5045097,0.0002553023],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.03765061,0.8647952,0.02394955,0.05510447,0.003521237,0.00006483405,0.0003541508,0.000121855,0.01443806],"genre_scores_gemma":[0.2521646,0.7006472,0.02119572,0.00773084,0.005526471,0.0001968128,0.0002932967,0.00003697034,0.01220827],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001997956,"threshold_uncertainty_score":0.006063163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02506193054854843,"score_gpt":0.2616584138158108,"score_spread":0.2365964832672623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}