{"id":"W2138926750","doi":"10.1093/annonc/mdf089","title":"First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous5-fluorouracil/leucovorin","year":2002,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":524,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation","funders":"","keywords":"Capecitabine; Medicine; Internal medicine; Neutropenia; Fluorouracil; Gastroenterology; Regimen; Adverse effect; Colorectal cancer; Nausea; Febrile neutropenia; Oncology; Surgery; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004167435,0.000242304,0.0007842096,0.0001582612,0.0001543656,0.0003728205,0.0001492013,0.0002653467,0.002590345],"category_scores_gemma":[0.001201555,0.0001086823,0.0004638532,0.0002565097,0.0001453476,0.0002389339,0.00009068826,0.000799269,0.0001681521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000484679,"about_ca_system_score_gemma":0.0004822821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007612914,"about_ca_topic_score_gemma":0.003012445,"domain_scores_codex":[0.9998701,0.00006426271,0.000007962581,0.00001260989,0.00002471073,0.00002039951],"domain_scores_gemma":[0.9995548,0.0001756709,0.0001292072,0.00002493392,0.00002099555,0.00009436807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2851337,0.00359214,0.03523627,0.00152267,0.001637025,0.001003694,0.0001776952,0.002483671,0.07878125,0.0004072082,0.003302045,0.5867228],"study_design_scores_gemma":[0.06926914,0.3113296,0.5287437,0.0003976483,0.004271005,0.008413035,0.0002361678,0.00775369,0.0529368,0.0006849064,0.01587811,0.00008629637],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873355,0.01049045,0.0002960977,0.0002893975,0.00005554328,0.0000519262,0.0002095922,0.00002170932,0.0012499],"genre_scores_gemma":[0.9955204,0.00302027,0.0002744086,0.0001135395,0.00005453825,0.00001684512,0.0002684175,0.000008767535,0.0007228624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002590345,"threshold_uncertainty_score":0.008665621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09844456695473171,"score_gpt":0.3593883428312434,"score_spread":0.2609437758765117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}