{"id":"W2138990885","doi":"10.1139/w2012-098","title":"Construction of recombinant lactobacilli expressing the core neutralizing epitope (COE) of porcine epidemic diarrhea virus and a fusion protein consisting of COE and<i>Escherichia coli</i>heat-labile enterotoxin B, and comparison of the immune responses by orogastric immunization","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Microbiology; Enterotoxin; Heat-labile enterotoxin; Porcine epidemic diarrhea virus; Immunogenicity; Biology; Virology; Lactobacillus casei; Escherichia coli; Recombinant DNA; Adjuvant; Epitope; Virus; Antibody; Bacteria; Immunology; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002293405,0.0004534033,0.0002532266,0.0001684612,0.0001185034,0.0002618618,0.0002262992,0.0002485455,0.0004253318],"category_scores_gemma":[0.0001870476,0.0001358681,0.0003207927,0.0002587459,0.0001367655,0.000206966,0.0003439774,0.0005100158,0.0001391292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353157,"about_ca_system_score_gemma":0.0002053136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000691223,"about_ca_topic_score_gemma":0.0006115947,"domain_scores_codex":[0.99983,0.00002779198,0.00002167143,0.00003023433,0.00004735607,0.00004298599],"domain_scores_gemma":[0.9999231,0.00001129028,0.00002693253,0.000009025434,0.000008266154,0.00002140684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007623217,0.00005940008,0.0001726693,0.00003533045,0.000006278409,0.00003552795,0.00001191534,0.00005387015,0.998836,0.00007499335,0.00001870703,0.0006191384],"study_design_scores_gemma":[0.00004609578,0.0008763904,0.003609807,0.000009231754,0.00004024059,0.0004428726,0.00006110054,0.001733514,0.99031,0.00004239869,0.002817529,0.00001084962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941818,0.0004482626,0.004018332,0.00005979936,0.00004364975,0.00007795299,0.00040468,0.00002930665,0.0007362282],"genre_scores_gemma":[0.9842099,0.0006071847,0.01048411,0.00005926548,0.00001049812,0.0001064316,0.002499102,0.00002937818,0.001994194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000691223,"threshold_uncertainty_score":0.001707375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03036285479432951,"score_gpt":0.2401178061800736,"score_spread":0.209754951385744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}